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Statistical phylogeography of Chagas disease vector Triatoma infestans: Testing biogeographic hypotheses of dispersal

Authordc.contributor.authorTorres Pérez, Fernando 
Authordc.contributor.authorAcuña Retamar, Mariana es_CL
Authordc.contributor.authorCook, Joseph A. es_CL
Authordc.contributor.authorBacigalupo, Antonella es_CL
Authordc.contributor.authorGarcía Mora, Alejandro es_CL
Authordc.contributor.authorCattan Ayala, Pedro es_CL
Cita de ítemdc.identifier.citationInfection, Genetics and Evolution 11 (2011) 167–174es_CL
General notedc.descriptionArtículo de publicación ISIes_CL
Abstractdc.description.abstractChagas disease is one of the most important vector-borne diseases in Latin America. The disease, caused by the flagellate protozoan Trypanosoma cruzi, is commonly transmitted to humans by Triatoma infestans in South America. Using mitochondrial DNA sequences, we assessed alternative biogeographic scenarios of dispersal of T. infestans using coalescence simulations. We also assessed phylogeographic structure and spatial genetics of T. infestans in Chile. Two major routes of dispersal in southern South America were supported including a dual-origin of T. infestans in Chile. Phylogeographic analyses identified two primary clades with Chilean haplotypes partitioned into either a northern cluster with Peruvian and Bolivian haplotypes or a north-central cluster with Argentinean and Uruguayan haplotypes. The northcentral clade is further divided into two subgroups. Domestic and sylvatic T. infestans in central Chile were not segregated in the phylogeographic reconstruction. Spatial genetic analyses show higher distances in northern Chile, congruent with the presence of two divergent lineages of T. infestans. Phylogenetic evidence does not unequivocally support the hypothesized Bolivian origin of T. infestans, so we discuss alternative scenarios.es_CL
Patrocinadordc.description.sponsorshipFondecyt 1070960.es_CL
Keywordsdc.subjectChagas diseasees_CL
Títulodc.titleStatistical phylogeography of Chagas disease vector Triatoma infestans: Testing biogeographic hypotheses of dispersales_CL
Document typedc.typeArtículo de revistaes_CL

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