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Positive association between conflicts of interest and reporting of positive results in randomized clinical trials in dentistry

Authordc.contributor.authorBrignardello Petersen, Romina 
Authordc.contributor.authorCarrasco Labra, Alonso es_CL
Authordc.contributor.authorYanine Montaner, Nicolás es_CL
Authordc.contributor.authorUlloa Marín, Carolina es_CL
Authordc.contributor.authorAraya Cabello, Ignacio es_CL
Authordc.contributor.authorPintor, Fernanda es_CL
Authordc.contributor.authorVillanueva Maffei, Julio es_CL
Authordc.contributor.authorCornejo Ovalle, Marco es_CL
Admission datedc.date.accessioned2014-01-14T13:42:28Z
Available datedc.date.available2014-01-14T13:42:28Z
Publication datedc.date.issued2013
Cita de ítemdc.identifier.citationJADA 2013;144(10):1165-1170en_US
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/123511
General notedc.descriptionArtículo de publicación ISIen_US
Abstractdc.description.abstractBackground. The relationship between industry funding and study results has been explored widely in medicine but not in dentistry. The authors aimed to assess the relationship between conflicts of interest (COIs) and study results. Methods. The authors assessed all randomized clinical trials (RCTs) published between July 2010 and June 2012 in the 10 dental journals with the highest impact factors in dentistry. The authors used three definitions of COI and explored their associations with positive study results. Results. Depending on the definition of COI, the odds ratio for reporting positive results varied between 2.40 (95 percent confidence interval [CI], 1.16-5.13) and 9.19 (95 percent CI, 1.71- 170.64). The authors found no association between positive study results and journal of publication or area of practice. Conclusions. RCTs in which authors have some type of COI are more likely to have results that support the intervention being assessed. Practical Implications. When reviewing the results of RCTs, clinicians need to be aware of the association between reporting positive study results and the type of COI disclosure and be even more careful when critically appraising and applying their results.en_US
Lenguagedc.language.isoenen_US
Publisherdc.publisherAmerican Dental Associationen_US
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Keywordsdc.subjectConflict of interesten_US
Títulodc.titlePositive association between conflicts of interest and reporting of positive results in randomized clinical trials in dentistryen_US
Document typedc.typeArtículo de revistaen_US


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile