The relative prevalence of schizophrenia among cannabis and cocaine users attending addiction services
Author
dc.contributor.author
Libuy Hidalgo, Nicolás
Author
dc.contributor.author
Angel, Valeria de
Author
dc.contributor.author
Ibáñez Berríos, Carlos
Author
dc.contributor.author
Murray, Robin M.
Author
dc.contributor.author
Mundt, Adrian P.
Admission date
dc.date.accessioned
2018-07-18T13:16:39Z
Available date
dc.date.available
2018-07-18T13:16:39Z
Publication date
dc.date.issued
2018
Cita de ítem
dc.identifier.citation
Schizophrenia Research, 194 (2018): 13–17
es_ES
Identifier
dc.identifier.other
10.1016/j.schres.2017.04.010
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/149979
Abstract
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Background: Cannabis and cocaine are the most common illicit drugs for which people are treated in addiction services in Latin America. Much research has suggested that the use of cannabis increases the risk of schizophrenia; there is less evidence concerning cocaine. The aim of the present study was to establish the relative prevalence of schizophrenia in people treated for cannabis use and cocaine use disorders in Chile.
Methods: A sample of 22,615 people treated for illicit drug use disorders was obtained from a national registry of addiction service users in Chile. Clinical diagnoses were established at admission to substance use treatment programs or at any point during the period of treatment. Prevalence rates of schizophrenia and related disorders, and affective disorders were calculated for the groups of people with cocaine use disorders, and cannabis use disorders. Odds ratios (OR) for schizophrenia and for affective disorders were calculated for cannabis users using the group of people treated for cocaine use disorders as reference category.
Results: The prevalence of schizophrenia and related disorders was 1.1% in those with cocaine use disorders, but 5.2% in those with cannabis use disorders (OR 4.9; p < 0.01). The prevalence of affective disorders was 9.3% in cocaine use disorders, and 13.2% in cannabis use disorders (OR 1.5; p < 0.01).
Conclusions: The prevalence of schizophrenia and to a lesser extent affective disorders is higher among people with cannabis use disorder than cocaine use disorder among those attending addiction services.
es_ES
Patrocinador
dc.description.sponsorship
Department of Health
RP-PG-0606-1049
Medical Research Council
MR/K013807/1
MR/K004867/1
G0700995
G1100583
G0600972