Author | dc.contributor.author | Rojas Garrido, María Cecilia | |
Author | dc.contributor.author | Gutierrez, Crisanto | |
Author | dc.contributor.author | Litvak, Simón | |
Author | dc.contributor.author | Solari Illescas, Aldo | |
Admission date | dc.date.accessioned | 2018-12-20T14:52:43Z | |
Available date | dc.date.available | 2018-12-20T14:52:43Z | |
Publication date | dc.date.issued | 1993 | |
Cita de ítem | dc.identifier.citation | International Journal for Parasitology, Volumen 23, Issue 3, 1993, Pages 361-364 | |
Identifier | dc.identifier.issn | 00207519 | |
Identifier | dc.identifier.other | 10.1016/0020-7519(93)90011-M | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/157203 | |
Abstract | dc.description.abstract | DNA synthesis in epimastigote forms of Trypanosoma cruzi was studied autoradiographically by incorporation of [3H]thymidine in the nuclear and kinetoplast DNA. Both DNA were heavily labelled. Three eukaryotic DNA polymerase inhibitors (aphidicolin, aracytidine, and dideoxythimidine) were chosen to study the nuclear and kinetoplast DNA synthesis in vivo. Inhibition was mainly observed with the nuclear DNA. | |
Lenguage | dc.language.iso | en | |
Source | dc.source | International Journal for Parasitology | |
Keywords | dc.subject | DNA polymerase inhibitors | |
Keywords | dc.subject | in vivo DNA synthesis | |
Keywords | dc.subject | Trypanosoma cruzi | |
Título | dc.title | Nuclear and kinetoplast DNA synthesis in Trypanosoma cruzi, autoradiographical study with DNA polymerase inhibitors | |
Document type | dc.type | Artículo de revista | |
Cataloguer | uchile.catalogador | apc | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |