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Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-κ B ligand, interleukin (IL) -17, IL-10 and transforming growth factor-β during the progression of chronic periodontitis

Authordc.contributor.authorDutzan, Nicolás 
Authordc.contributor.authorGamonal Aravena, Jorge Antonio 
Authordc.contributor.authorSilva, Augusto 
Authordc.contributor.authorSanz, Mariano 
Authordc.contributor.authorVernal Astudillo, Rolando 
Admission datedc.date.accessioned2018-12-20T15:22:36Z
Available datedc.date.available2018-12-20T15:22:36Z
Publication datedc.date.issued2009
Cita de ítemdc.identifier.citationJournal of Clinical Periodontology, Volumen 36, Issue 5, 2018, Pages 396-403
Identifierdc.identifier.issn03036979
Identifierdc.identifier.issn1600051X
Identifierdc.identifier.other10.1111/j.1600-051X.2009.01390.x
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/158925
Abstractdc.description.abstractDutzan N, Gamonal J, Silva A, Sanz M, Vernal R. Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-κ B ligand, interleukin (IL)-17, IL-10 and transforming growth factor-β during the progression of chronic periodontitis. J Clin Periodontol 2009; 36: 396-403. doi: 10.1111/j.1600-051X.2009.01390.x. Abstract Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-κ B ligand (RANKL). The aim of this study was to correlate T-helper type 1 (Th1), Th2, Th17 and Treg transcription factor expressions, in gingival tissues from patients undergoing active periodontal tissue destruction, with bone loss-associated cytokines. Materials and Methods: In 10 chronic periodontitis patients undergoing disease progression, the mRNA expressions of T-bet, GATA-3, Foxp3, RORC2, interleukin (IL)-1β, IL-10, IL-17, RANKL, interferon (IFN)-γ
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceJournal of Clinical Periodontology
Keywordsdc.subjectCD25
Keywordsdc.subjectCTLA-4
Keywordsdc.subjectFoxp3
Keywordsdc.subjectIL-17
Keywordsdc.subjectPeriodontitis
Keywordsdc.subjectRANKL
Keywordsdc.subjectRegulatory T cells
Keywordsdc.subjectRORC2
Keywordsdc.subjectTreg
Títulodc.titleOver-expression of forkhead box P3 and its association with receptor activator of nuclear factor-κ B ligand, interleukin (IL) -17, IL-10 and transforming growth factor-β during the progression of chronic periodontitis
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile