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Authordc.contributor.authorAbusleme Ramos, Loreto Andrea 
Authordc.contributor.authorO'Gorman, H. 
Authordc.contributor.authorDutzan Muñoz, Nicolás 
Authordc.contributor.authorGreenwell-Wild, T. 
Authordc.contributor.authorMoutsopoulos, N. M. 
Admission datedc.date.accessioned2020-06-15T22:51:46Z
Available datedc.date.available2020-06-15T22:51:46Z
Publication datedc.date.issued2020
Cita de ítemdc.identifier.citationJ Dent Res 2020 Jun ; 99 (6): 721-729es_ES
Identifierdc.identifier.other10.1177/0022034520915485
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/175490
Abstractdc.description.abstractCommensal microbiomes exert critical functions at barrier sites. In particular, establishment of the commensal microbiome after birth dictates immune functionality and tissue homeostasis at mucosal surfaces. To investigate the establishment and stability of the oral mucosal microbiome in mice, we evaluated oral microbiome communities shortly after birth, through adulthood, and up to 1 y of life in a controlled manner, using sequential oral samples from the same mice over time. We further evaluated transmissibility of oral microbiomes from parents and during cohousing experiments and evaluated susceptibility to oral inflammatory disease in mice harboring distinct microbiomes. Our work reveals basic principles in the establishment and stability of a health-associated oral microbiome after birth and provides insights that may be important for host-microbiome experimentation in animal models.es_ES
Patrocinadordc.description.sponsorshipIntramural Program of the National Institute of Dental and Craniofacial Research (NIDCR)/National Institutes of Health (NIH) Comisión Nacional de Investigación Científica y Tecnológica (CONICYT) CONICYT FONDECYT 11180505 11180389es_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherSAGEes_ES
Sourcedc.sourceJournal of Dental Researches_ES
Keywordsdc.subjectMicrobiome establishmentes_ES
Keywordsdc.subjectMicrobiome transferes_ES
Keywordsdc.subjectMicrobiome stabilityes_ES
Keywordsdc.subjectOral microbial acquisitiones_ES
Keywordsdc.subjectOral mucosal microbiomees_ES
Keywordsdc.subjectGingival microbiomees_ES
Títulodc.titleEstablishment and Stability of the Murine Oral Microbiomees_ES
Document typedc.typeArtículo de revistaes_ES
Catalogueruchile.catalogadorctces_ES
Indexationuchile.indexArtículo de publicación ISIes_ES
Access notedct.AccessRightsSin acceso a texto completoes_ES


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