Browsing by Title

Now showing items 13205-13224 of 92398

    • CD4+Foxp3+T regulatory cells promote transplantation tolerance by modulating effector CD4+ T cells in a ... 
      Campos-Mora, Mauricio; Contreras-Kallens, Pamina; Gálvez-Jirón, Felipe; Rojas, Masyelly; Rojas, Carolina; Refisch, Aarón; Cerda, Oscar; Pino-Lagos, Karina (Frontiers Media S.A., 2019)
      Copyright © 2019 Campos-Mora, Contreras-Kallens, Gálvez-Jirón, Rojas, Rojas, Refisch, Cerda and Pino-Lagos.Several mechanisms of immune suppression have been attributed to Foxp3+ T regulatory cells (Treg) including modulation ...
    • CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression 
      Bono Merino, María Rosa; Fernández, Dominique; Flores Santibáñez, Felipe; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela (Elsevietr, 2015)
      Extracellular ATP is a danger signal released by dying and damaged cells, and it functions as an immunostimulatory signal that promotes inflammation. However, extracellular adenosine acts as an immunoregulatory signal that ...
    • CD73 ectonucleotidase restrains CD8+T cell metabolic fitness and anti-tumoral activity 
      Briceño Catalán, Pedro Felipe; Rivas Yáñez, Elizabeth Camila; Rosemblatt Bono, Mariana Violeta; Parra Tello, Brian Josué; Farías, Paula; Vargas, Leonardo; Simon Zegers, María Valeska; Cárdenas, César; Lladser, Álvaro; Salazar Onfray, Flavio Andrés; Elorza, Álvaro A.; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; Sauma Mahaluf, Daniela Macarena (Frontiers Media, 2021)
      CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ...
    • CD73 presente en linfocitos T CD8+ favorece su proliferación homeostática e inhibe su capacidad efectora 
      Rosemblatt Bono, Mariana (Universidad de Chile, 2020)
      La respuesta inmune mediada por los linfocitos T (LT) CD8+ requiere que estas células sean capaces de diferenciarse hacia células efectoras citotóxicas y de memoria que puedan producir una respuesta cada vez más efectiva. ...
    • CD73 restringe la adquisición de un fenotipo efector en linfocitos TCD8+. 
      Briceño Catalán, Pedro Felipe (Universidad de Chile., 2021)
      La adenosina es un nucleósido que inhibe la activación y función de los linfocitos T CD8+. Se ha descrito que la señalización de adenosina por medio del receptor A2A, regula negativamente las señales derivadas del ...
    • CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells 
      Flores Santibáñez, Felipe; Fernández, Dominique; Meza, Daniel; Tejón, Gabriela; Vargas, Leonardo; Varela Nallar, Lorena; Arredondo, Sebastián; Guixé Leguía, Victoria Cristina; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; Sauma Mahaluf, Daniela (Wiley & Sons, 2015)
      The CD73 ectonucleotidase catalyses the hydrolysis of AMP to adenosine, an immunosuppressive molecule. Recent evidence has demonstrated that this ectonucleotidase is up-regulated in T helper type 17 cells when generated in ...
    • CDA: Centro de Difusión Astronómica Universidad de Chile: Observatorio Astronómico Nacional Cerro Calán 
      Urrutia Beiza, Ricardo (Universidad de Chile, 2012)
    • CDETQ: — centro de desarrollo económico territorial Quilicura 
      Solar, Alejandro (Universidad de Chile, 2006)
    • Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate 
      Araya, Claudio; Häkkinen, Hanna Maria; Carcamo, Luis; Cerda, Mauricio; Savy, Thierry; Rookyard, Christopher; Peyriéras, Nadine; Clarke, Jonathan D.W. (Nature Publishing Group, 2019)
      Tissue internalisation is a key morphogenetic mechanism by which embryonic tissues generate complex internal organs and a number of studies of epithelia have outlined a general view of tissue internalisation. Here we have ...
    • CDK5 downregulation enhances synaptic plasticity 
      Posada Duque, Rafael; Ramírez, Omar A.; Härtel, Steffen; Inestrosa, Nibaldo C.; Bodaleo, Felipe; González Billault, Christian; Kirkwood, Alfredo; Cardona Gómez, Gloria (Birkhauser Verlag AG, 2017)
      © 2016, Springer International Publishing. CDK5 is a serine/threonine kinase that is involved in the normal function of the adult brain and plays a role in neurotransmission and synaptic plasticity. However, its over-regulation ...
    • cdk5 modulates β- and δ-catenin/Pin1 interactions in neuronal cells 
      Muñoz, Juan P.; Huichalaf, Claudia H.; Orellana, Daniel; Maccioni Baraona, Ricardo (2007)
      The cdk5/p35 complex has been implicated in a variety of functions related to brain development, including axonal outgrown and neuronal migration. In this study, by co-immunoprecipitation and pull-down experiments, we have ...
    • Cdk5 regulates Rap1 activity 
      Utreras Puratich, Elías; Henríquez, Daniel R.; Contreras Vallejos, Erick; Olmos, Cristina; Di Genova, Alex; Maass Sepúlveda, Alejandro; Kulkarni, Ashok B.; González Billault, Christian (2013)
      Rap1 signaling is important for migration, differentiation, axonal growth, and during neuronal polarity. Rap1 can be activated by external stimuli, which in turn regulates specific guanine nucleotide exchange factors such ...
    • Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth 
      Furusawa, Kotaro; Asada, Akiko; Urrutia, Pamela; González Billault, Christian; Fukuda, Mitsunori; Hisanaga, Shin-ichi (Society for Neuroscience, 2017)
      Neurons communicate with each other through their axons and dendrites. However, a full characterization of the molecular mechanisms involved in axon and dendrite formation is still incomplete. Neurite outgrowth requires ...
    • CDK5: A Unique CDK and Its Multiple Roles in the Nervous System 
      Cortés, Nicole; Guzmán Martínez, Leonardo; Andrade, Víctor; González, Andrea; Maccioni Baraona, Ricardo (IOS Press, 2019)
      The cyclin-dependent kinase 5 (CDK5) is known as an exceptional component of the CDK family, due to its characteristic regulatory pathways and its atypical roles in comparison to the classical cyclins. Despite its functional ...
    • CDM: centro integral para el desarrollo de la infancia y la maternidad 
      Serres Gómez, Marcelo (Universidad de Chile, 2007)
      Para los sectores en mayor riesgo social, el párvulo (jardín infantil y/o sala cuna) a modo de tipología programática como clásicamente se le conoce (impartiendo solo educación formal para niños y cuidados a nivel de ...
    • CdS QDs-Decorated Self-Doped gamma-Bi2MoO6: a sustainable and versatile photocatalyst toward photoreduction ... 
      Kandi, Debasmita; Martha, Satyabadi; Thirumurugan, Arun; Parida, K. M. (American Chemical Society, 2017)
      In this work, CdS quantum dots (QDs)-sensitized self-doped Bi2MoO6 has been synthesized using glucose as reducing agent by hydrothermal method, followed by in situ deposition of the QDs. The synthesized catalyst has been ...
    • CDV. Centro de Desarrollo Vitivinícola, Santa Cruz. 
      Sabat, Rodrigo (Universidad de Chile, 2004)
      El vino chileno ha alcanzado un lugar destacado dentro de la industria vitivinícola internacional. Se ha destacado con productos de calidad y más que nada por su excelente relación precio-calidad. Los factores climáticos y ...
    • CDVCH Centro de difusión del vino chileno 
      Salas Vargas, Natalia E. (Universidad de ChileCyberDocs, 2011)
      El estudiar el vino como tema para proyecto de titulo, hizo posible la realización de diversas visitas a varias viñas del país. Estas experiencias permitieron la observación de un fenómeno particular: La mayoría de los ...
    • CE 315: a new interacting double-degenerate binary star 
      Ruiz González, María Teresa; Rojo Rubke, Patricio; Garay Brignardello, Guido; Maza Sancho, José (UNIV CHICAGO PRESS, 2001-05-10)
      We present spectroscopic observations of object CE 315 revealing a blue continuum with strong emission lines. Most of the detected lines are identified with He I or He II in emission, with a handful of faint lines of ...
    • CEAC : proyecto de con-formación centro de extensión artística y cultural, campus Andrés Bello - Universidad ... 
      Segura Ahumada, Ximena (Universidad de Chile, 2004)
      Este proyecto de título, pretende contribuir la retroalimentación que se produce entre la Universidad como entidad fundamental en el desarrollo de la identidad nacional,y la ciudad, generando distintos grados de encuentro ...