Browsing by Author "Lagos Mónaco, Rosalba"
Now showing items 1-20 of 20
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(ELSEVIER SCIENCE INC, 2007-09-15)FtsZ (Filamentous temperature sensitivity Z) cell division protein from Escherichia coli binds the fluorescence probe DAPI. Bundling of FtsZ was facilitated in the presence of DAPI, and the polymers in solution remained ...
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(Universidad de Chile, 2008)
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(Universidad de Chile, 2006)EI uso de enzimas adaptadas/activas a bajas temperaturas tiene un alto potencial en terminos de menores costos energeticos, aplicaciones terapeuticas y menor contaminacion microbiana en procesos industriales. Las bacterias ...
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(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2005-07-22)The aggregation of proteins into amyloid fibrils is the hallmark feature of a group of late-onset degenerative diseases including Alzheimer, Parkinson, and prion diseases. We report here that microcin E492, a peptide ...
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(Universidad de Chile, 2018)En las últimas dos décadas, la especie bacteriana Klebsiella pneumoniae se ha convertido en uno de los principales focos de atención de las autoridades mundiales de salud, debido principalmente a la rápida aparición de ...
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(Universidad de Chile, 2024)La transferencia horizontal de genes, mediada por elementos genéticos móviles (EGMs) ha sido uno de los mecanismos por los que el genoma bacteriano ha evolucionado. En cepas con relevancia clínica, este tipo de transferencia ...
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(2009)Microcins are a family of low-molecular weight bacteriocins produced and secreted by Gram-negative bacteria. This review is focused on microcin E492, a pore-forming bacteriocin produced by Klebsiella pneumoniae RYC492 that ...
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Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly (Elsevier, 2015)Dihydroxynaphthyl aryl ketones 1e5 have been evaluated for their abilities to inhibit microtubule assembly and the binding to tubulin. Compounds 3, 4 and 5 displayed competitive inhibition against colchicine binding, and ...
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(Universidad de Chile, 2010)Durante la citoquinesis bacteriana, en el sitio de división se forma un polímero de FtsZ llamado el anillo Z cuya constricción contribuye a la división de la célula para dar origen a dos células hijas. Por esto, Ftsz es ...
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(Universidad de Chile, 2003)La FtsZ polimeriza para formar el anillo Z alrededor del perímetro transversal en el centro de la célula cuando la bacteria E. coli inicia la formación del septo. En este proceso participan varias proteínas Fts para formar ...
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(COLD SPRING HARBOR LAB PRESS, 2007-08)FtsZ has two domains, the amino GTPase domain with a Rossmann fold, and the carboxyl domain that resembles the chorismate mutase fold. Bioinformatics analyses suggest that the interdomain interaction is stronger than the ...
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(COLD SPRING HARBOR LAB PRESS, 2006-03)The goal of this work was to determine the binding properties and location of 4',6-diamidino-2-phenyl=indole (DAPI) complexed with tubulin. Using fluorescence anisotropy, a dissociation constant of 5.2 +/- 0.4 mu M for the ...
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(Frontiers Media S.A., 2016)Microcin E492 (MccE492) is a pore-forming bacteriocin produced and exported by Klebsiella pneumoniae RYC492. Besides its antibacterial activity, excreted MccE492 can form amyloid fibrils in vivo as well as in vitro. It has ...
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(Universidad de Chile, 2022)Klebsiella pneumoniae (Kpn) is considered an urgent health threat due to the emergence of multidrug-resistant and hypervirulent strains attributed to the acquisition of mobile genetic elements (MGEs). One MGE possibly ...
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(American Society for Microbiology, 2013)Microcin E492, a channel-forming bacteriocin with the ability to form amyloid fibers, is exported as a mixture of two forms: unmodified (inactive) and posttranslationally modified at the C terminus with a salmochelin-like ...
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(Universidad de Chile, 2009)Las bacteriocinas son antibióticos de naturaleza peptídica producidas por un amplio espectro de bacterias Gram positiva y negativa. La microcina E492 (MccE492) es una bacteriocina formadora de poros producida por Klebsiella ...
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(1996)Pharmacokinetics of a long-acting formula of oxytetracycline (OTC) in one formulation of dymetylacetomide, was studied in seven-cows after i.m. administration (20 mg/kg of body weight). Serum OTC concentration was measured ...
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The production in vivo of microcin E492 with antibacterial activity depends on salmochelin and EntF (AMER SOC MICROBIOLOGY, 2008-08)Microcin E492 is a channel-forming bacteriocin that is found in two forms, namely, a posttranslationally modified form obtained by the covalent linkage of salmochelin-like molecules to serine 84 and an unmodified form. ...
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(Elsevier, 2014)Cell division protein FtsZ cooperatively self-assembles into straight filaments when bound to GTP. A set of conformational changes that are linked to FtsZ GTPase activity are involved in the transition from straight to ...
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(2012-05)FtsZ is a major protein in bacterial cytokinesis that polymerizes into single filaments. A dimer has been proposed to be the nucleating species in FtsZ polymerization. To investigate the influence of the self-assembly of ...
