Now showing items 1-4 of 4

    • Ortiz, Andrea C.; Yáñez, Osvaldo; Salas Huenuleo, Edison Sebastián; Morales Montecinos, Javier Octavio (MDPI, 2021)
      Lipid nanocarriers have a great potential for improving the physicochemical characteristics and behavior of poorly water-soluble drugs, such as aqueous dispersibility and oral bioavailability. This investigation presents ...
    • Morales Montecinos, Javier Octavio (Universidad de Chile, 2007)
      En esta tesis se estudió el efecto que tendrían la βCD y la 2,6-DMβCD sobre la solubilidad de un nuevo nitroderivado antichagásico, el 1-(2-(dimetilamino)etil)-3-metoxi-5- nitro-1H-indazol. Además se propuso la estructura ...
    • Sepúlveda Rivas, Sabrina; Leal, Matías S.; Pedrozo Cibils, Zully Rocío Evangelina; Kogan, Marcelo Javier; Ocaranza Jeraldino, María Paz Alejandra; Morales Montecinos, Javier Octavio (MDPI, 2021)
      Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced ...
    • Sánchez, Sofía V.; Navarro Martínez, Nicolás Matías; Catalán Figueroa, Johanna; Morales Montecinos, Javier Octavio (Frontiers Media, 2021)
      Urinary tract infection (UTI) is one of the most common reasons for antibiotic treatment. Nevertheless, uropathogens are steadily becoming resistant to currently available therapies. In this context, nanotechnology emerges ...