Browsing by Title Facultad de Ciencias Químicas y Farmacéuticas

Now showing items 2807-2826 of 4850

    • El inhibidor de rock, fasudil y el antidepresivo sertralina comparten efectos a nivel morfológico y molecular ... 
      García Rojo, Gonzalo Javier (Universidad de Chile, 2017)
      La depresión es un trastorno psiquiátrico muy prevalente en Chile y el mundo. Sus bases moleculares son prácticamente desconocidas, por lo que los tratamientos farmacológicos no han logrado ser del todo efectivos. En la ...
    • Inhibition and activation of UDP-glucuronyltransferase in alloxanic-diabetic rats 
      Vega, Patricio; Gaule, Carlos; Sanchez, Emilio; Villar, Eugenia del (1986)
      Short or long term alloxan diabetes produced activation of oestrone and morphine glucuronidation and inhibition of p-nitrophenol glucuronidation in rat liver microsomes. Insulin treatment restored decreased glucuronyltransferase ...
    • Inhibition of autophagy by TAB2 and TAB3 
      Criollo Céspedes, Alfredo; Niso-Santano, Mireia; Malik, Shoaib Ahmad; Michaud, Mickael; Morselli, Eugenia; Mariño, Guillermo; Lachkar, Sylvie; Arkhipenko, Alexander V.; Harper, Francis; Pierron, Gérard; Rain, Jean Christophe; Ninomiya-Tsuji, Jun; Fuentes, José M.; Lavandero González, Sergio (2011)
      Autophagic responses are coupled to the activation of the inhibitor of NF-κB kinase (IKK). Here, we report that the essential autophagy mediator Beclin 1 and TGFβ-activated kinase 1 (TAK1)-binding proteins 2 and 3 (TAB2 ...
    • Inhibition of beta-amyloid Aggregation of Ugni molinae Extracts 
      Jara Moreno, Daniela; Riveros Salvatierra, Ana L.; Barriga G., Andrés; Kogan, Marcelo J.; Delporte Vergara, Carla (Bentham Science Publishers, 2020)
      The beta-amyloid peptide (1-42) is a molecule capable of aggregating into neurotoxic structures that have been implicated as potential etiological factors of Alzheimer's Disease. The aim of this study was to evaluate the ...
    • Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression 
      Morales, Cyndi R.; Li, Dan L.; Pedrozo Cibils, Zully; May, Herman I.; Jiang, Nan; Kyrychenko, Viktoriia; Cho, Geoffrey; Kim, Soo Young; Wang, Zhao V.; Rotter, David; Rothermel, Beverly A.; Schneider, Jay W.; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Amer Assoc Advancement Science, 2016)
      Altering chromatin structure through histone posttranslational modifications has emerged as a key driver of transcriptional responses in cells. Modulation of these transcriptional responses by pharmacological inhibition ...
    • Inhibition of cytosolic glutathione S-transferase activity from rat liver by copper 
      Letelier Muñoz, María Eugenia; Martínez, M.; González Lira, Víctor; Faúndez, Mario; Aracena Parks, Paula (ELSEVIER, 2006-12-01)
      H2O2 inactivation of particular GST isoforms has been reported, with no information regarding the overall effect of other ROS on cytosolic GST activity. The present work describes the inactivation of total cytosolic GST ...
    • Inhibition of HIV-2(ROD) replication in a lymphoblastoid cell line by the alpha 1-antitrypsin Portland ... 
      Bahbouhi, B.; Bendjennat, M.; Chiva, C.; Kogan Bocian, Marcelo; Albericio, F.; Giralt, Ernest; Seidah, N. G.; Bahraoui, E. (EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2001-11)
      We investigated the effects of alpha1-antitrypsine Portland variant (alpha1-PDX) and decanoylRVKRchloromethylketone (decRVKRcmk) on HIV-2(ROD) replication in the Jurkat lymphoblastoid cell line. To this end, cells were ...
    • Inhibition of soybean 15-lipoxygenase and human 5-lipoxygenase by extracts of leaves, stem bark, phenols ... 
      Muñoz Ramírez, Alejandra; Mascayano Collado, Carolina; Barriga, Andrés; Echeverría, Javier; Urzúa, Alejandro (Frontiers Media, 2020)
      Lithraea caustica (Molina) Hook. and Arn. (Anacardiaceae), common name Litre, is an evergreen endemic plant used in the Mapuche Chilean folk medicine. The stem juice of L. caustica mixed with Rubus ulmifolius (blackberry) ...
    • Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by ... 
      Ponnappa, Biddanda C.; Israel Jacard, Yedy; Aini, María; Zhou, Feng; Russ, Rachel; Cao, Qing-na; Yiyang, Hu; Rubin, Raphael (PERGAMON-ELSEVIER SCIENCE LTD, 2005-02-15)
      Elevated serum tumor necrosis factor alpha JNF-alpha) levels predict mortality in patients with alcoholic liver disease. Administration of anti-TNF-alpha antibodies, obliteration of Kupffer cells or gut sterilization protect ...
    • Inhibition of tumoral cell respiration and growth by nordihydroguaiaretic acid 
      Pavani, M.; Fones, Elizabeth; Oksenberg Reisberg, Danny; García, Manuel; Hernández, Carolina; Cordano, Gianni; Muñoz, Sergio; Mancilla, Jerson; Guerrero, Aanibal; Ferreira Parker, Jorge (PERGAMON-ELSEVIER SCIENCE LTD, 1994-11-16)
      The effects of nordihydroguaiaretic acid (NDGA), best known as an inhibitor of lipoxygenase activities, on the culture growth, oxygen consumption, ATP level, viability, and redox state of some electron carriers of intact ...
    • Inhibitory effect of vanillin-like compounds on respiration and growth of adenocarcinoma TA3 and its ... 
      Cordano, G.; Pezoa Olivares, Jacqueline; Muñoz, S.; Rivera, E.; Medina, Jorge; Núñez Vergara, Luis; Pavani, Mario; Guerrero A., Aníbal; Ferreira Parker, Jorge (ELSEVIER SCIENCE BV, 2002-09)
      The effects of some imine and amine derivatives of vanillin on the respiration rate of mouse mammary adenocarcinoma TA3 line, its multiresistant variant TA3-MTX-R line and mouse hepatocytes, together with their respective ...
    • Inkjet Printing of Proteins: an Experimental Approach 
      Montenegro-Nicolini, Miguel; Miranda, Víctor; Morales, Javier O. (Springer New York LLC, 2017)
      © 2016, American Association of Pharmaceutical Scientists. Peptides and proteins represent a promissory group of molecules used by the pharmaceutical industry for drug therapy with great potential for development. However, ...
    • Inmovilización de 7-amino-β-ciclodextrinas utilizando derivados de ácido pireno-1-carboxílico : aplicación ... 
      Rojas Mora, Ximena Liliana (Universidad de Chile, 2024)
      En la presente memoria de título, se reportan los resultados de dos estrategias electroquímicas de modificación de electrodos: una denominada Botton-up y la otra “compósito”, aplicadas a superficies de electrodos de carbono ...
    • An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose ... 
      Contreras Ferrat, Ariel Eduardo; Toro, Barbra; Bravo, R.; Parra Ortíz, María Valentina; Vásquez, C.; Ibarra, Cristián; Mears, David; Chiong Lay, Mario; Jaimovich Pérez, Enrique; Klip, Amira; Lavandero González, Sergio (ENDOCRINE SOC, 2010-10)
      Intracellular calcium levels ([Ca2+](i)) and glucose uptake are central to cardiomyocyte physiology, yet connections between them have not been studied. We investigated whether insulin regulates [Ca2+](i) in cultured ...
    • The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 
      Vicencio, José Miguel; Ortíz, C.; Criollo Céspedes, Alfredo; Jones, A. W. E.; Kepp, O.; Galluzzi, Lorenzo; Joza, N.; Vitale, I.; Morselli, E.; Tailler, M.; Castedo, M.; Maiuri, M. C.; Molgó, Jordi; Szabadkai, G.; Lavandero González, Sergio; Kroemer, Guido (NATURE PUBLISHING GROUP, 2009-07)
      The inositol 1,4,5-trisphosphate receptor (IP3R) is a major regulator of apoptotic signaling. Through interactions with members of the Bcl-2 family of proteins, it drives calcium (Ca2+) transients from the endoplasmic ...
    • The inositol trisphosphate receptor in the control of autophagy 
      Criollo Céspedes, Alfredo; Vicencio, José Miguel; Tasdemir, E.; Maiuri, M. C.; Lavandero González, Sergio; Kroemer, Guido (LANDES BIOSCIENCE, 2007-07)
      The second messenger myo-inositol-1,4,5-trisphosphate (IP3) acts on the IP3 receptor (IP3R), an IP3-activated Ca2+ channel of the endoplasmic reticulum (ER). The IP3R agonist IP3 inhibits starvation-induced autophagy. The ...
    • Inscripción de un establecimiento importador de productos de higiene, bajo riesgo y odorizantes; declaración ... 
      Pávez Valenzuela, Camila Pilar (Universidad de Chile, 2014)
      Los productos cosméticos están regulados en Chile por el reglamento nacional de productos cosméticos aprobado por el Decreto Supremo N° 239 del año 2002. Dicho reglamento establece las bases para su fabricación, importación ...
    • Insights into the HyPer biosensor as molecular tool for monitoring cellular antioxidant capacity 
      Hernández, Helen; Parra, Alejandra; Tobar, Nicolas; Molina, Jessica; Kallens, Violeta; Hidalgo, Miltha; Varela, Diego; Martínez, Jorge; Porras Espinoza, Omar (Elsevier B.V., 2018)
      © 2018 The Authors Aerobic metabolism brings inexorably the production of reactive oxygen species (ROS), which are counterbalanced by intrinsic antioxidant defenses avoiding deleterious intracellular effects. Redox balance ...
    • Insights of the formation mechanism of nanostructured titanium oxide polymorphs from different macromolecular ... 
      Allende, Patricio; Orera, Alodia; Laguna Bercero, Miguel A.; Valenzuela, María Luisa; Díaz, Carlos; Barrientos, Lorena (Elsevier, 2021)
      The insight into the mechanism of the unprecedented formation of pure anatase TiO2 from the macromolecular (Chitosan)center dot(TiOSO4)(n) precursor has been investigated using micro Raman spectroscopy, Scanning Electron ...
    • Instauración de cultura del medicamento y su uso racional en la población extranjera de la comuna de ... 
      Allende Sepúlveda, Mario Esteban (Universidad de Chile, 2016)