Now showing items 5408-5427 of 12946

    • Soto Moyano, Rubén; Hernández, A.; Pérez, H.; Ruiz, S.; Carreño, P.; Belmar, J. (1993)
      It is known that nutritional restriction during gestation affects the growth of the corpus callosum. The present study was designed to evaluate whether prenatal malnutrition may alter, in the rat, the normal pattern of ...
    • Jansen, Jurgen; Friesema, Edith C. H.; Kester, Monique H. A.; Milici, Carmelina; Reeser, Maarten; Grüeters, Annette; Barrett, Timothy G.; Mancilla Vergara, Edna; Svensson, Johan; Wemeau, Jean-Louis; Busi da Silva Canalli, Maria Heloisa; Lundgren, Johan; McEntagart, Meriel E.; Hopper, Neil; Arts, Willem Frans; Visser, Theo J. (2007)
      Context: T-3 action in neurons is essential for brain development. Recent evidence indicates that monocarboxylate transporter 8 (MCT8) is important for neuronal T-3 uptake. Hemizygous mutations have been identified in the ...
    • Marín Catalán, Rigoberto; Riquelme Pino, Gloria; Godoy, V.; Díaz Moreno, Pablo; Abad, C.; Caires, R.; Proverbio, T.; Piñero, S.; Proverbio, F. (W B SAUNDERS CO LTD, 2008-08)
      It is known that human syncytiotrophoblast (hSCT) actively transports more than 80% of the Ca2þ that goes from maternal to fetal circulation. Transepithelial transport of Ca2þ is carried out through channels, transporters ...
    • Macqueen, Daniel J.; Primmer, Craig R.; Iturra Constant, Iris; Maass Sepúlveda, Alejandro; Yáñez López, José (BIOMED Central Ltd., 2017)
      We describe an emerging initiative - the 'Functional Annotation of All Salmonid Genomes' (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in the salmonid ...
    • Castillo, Viviana; Valenzuela, Rodrigo; Huidobro Alvarado, Christian; Contreras, Héctor R.; Castellón, Enrique A. (Spandidos, 2014)
      Cancer stem cells (CSCs) have the ability to self-renew and differentiate to give rise to heterogeneous phenotype of the tumor cells. It is believed that these cells are involved in metastasis, recurrence and therapy ...
    • Matus, Soledad; López, Estefanía; Valenzuela, Vicente; Nassif, Melissa; Hetz Flores, Claudio (PUBLIC LIBRARY SCIENCE, 2013-07-18)
      Endoplasmic reticulum (ER) stress represents an early pathological event in amyotrophic lateral sclerosis (ALS). ATF4 is a key ER stress transcription factor that plays a role in both adaptation to stress and the activation ...
    • Ricu, Manuel; Paredes, Alfonso; Greiner, Monika; Ojeda, Sergio R.; Lara Peñaloza, Hernán (2008)
      A substantial fraction of the noradrenergic innervation targeting the mammalian ovary is provided by neurons of the celiac ganglion. Although studies in the rat have shown that noradrenergic nerves reach the ovary near the ...
    • Rodrigo Cabezón, A.; Constanza Ramírez, R.; Pedro Badía, V.; Norma León, M.; Ximena Fonseca, A. (2011)
      Background: Swallowing disorders are common in hospitalized patients. Functional endoscopic evaluation of swallowing (FEES) is a simple, safe and effective test for the diagnosis and monitoring of these disorders. Aim: To ...
    • Mendoza Naranjo, Ariadna; Bouma, Gerben; Pereda, Cristián; Ramiŕez, Marcos; Webb, Kevin F.; Tittarelli, Andrés; Loṕez, Mercedes N.; Kalergis, Alexis M.; Thrasher, Adrian J.; Becker, David L.; Salazar Onfray, Flavio (2011)
      Gap junction (GJ) mediates intercellular communication through linked hemichannels from each of two adjacent cells. Using human and mouse models, we show that connexin 43 (Cx43), the main GJ protein in the immune system, ...
    • Mendoza Naranjo, Ariadna; Sáez, Pablo J.; Johansson, C. Christian; Ramírez Fernández, Marcos; Mandakovic Seyler, Dinka; Pereda, Cristián; López Nitsche, Mercedes; Kiessling, Rolf; Sáez, Juan C.; Salazar Onfray, Flavio (2007)
      Previously, we found that human dendritic cells (hDCs) pulsed with a melanoma cell lysate (MCL) and stimulated with TNF-ce (MCL/TNF) acquire a mature phenotype in vitro and are able to trigger tumor-specific immune responses ...
    • Olivares Paz, Alberto; Jofré Madariaga, David; Alvarez Mazú, Carlos; Bustos Obregón, Eduardo (2009)
      The coast of the Southeastern Pacific is the habitat for 13 species of described keyhole limpets of the subgenus Fissurella Brugière. In these species sexual dimorphism does not exist, the animals are dioicos, the sex is ...
    • Gutiérrez-Ibáñez, Cristián; Iwaniuk, Andrew N.; Lisney, Thomas J.; Faunes, Macarena; Marín, Gonzalo J.; Wylie, Douglas R. (Public Library of Science, 2012)
      In birds, there is a retinofugal projection from the brain to the retina originating from the isthmo optic nucleus (ION) in the midbrain. Despite a large number of anatomical, physiological and histochemical studies, the ...
    • Muñoz, Juan Pablo; González, Carolina; Parra, Bárbara; Corvalán, Alejandro H.; Tornesello, Maria Lina; Eizuru, Yoshito; Aguayo, Francisco (2012)
      The smoking habit is the most important, but not a sufficient cause for lung cancer development. Several studies have reported the human papillomavirus type 16 (HPV16) presence and E6 and E7 transcripts expression in lung ...
    • Vega Vega, Luis Felipe; Carrasco,; Castillo, Andrea; Troncoso, Sofía; Videla, Ximena; Devoto, Luigi (BioScientifica Ltd., 1995)
      To evaluate the effect of reactive oxygen species in human corpus luteum function, we investigated whether hydrogen peroxide (H2O2) affects the in vitro luteal cell production of steroids. H2O2 treatment (1.0-100 μM) of ...
    • Reyes, Roberto; Jaimovich Pérez, Enrique (Academic Press Inc., 1996)
      We studied the influence of muscarinic and nicotinic stimulation on both phosphoinositide metabolism and intracellular calcium levels in rat skeletal muscle primary cultures. Both nicotine and muscarine induced an increase ...
    • Cuadra, Alvaro; Correa, Gerardo; Roa, Ricardo; Piñeros, José Luis; Norambuena, Hernán; Searle, Susana; Las Heras, Rocío; Calderón, Wilfredo (Elsevier, 2012-02)
      Summary Introduction: Dermal substitutes, such as Integra introduced as a new alternative to our surgical arsenal and its use in burn treatment, in both acute and chronic phases, have gained great importance. Objective: ...
    • Castillo, Valentina; Oñate, Maritza G.; Woehlbier, Ute; Rozas, Pablo; Andreu, Catherine; Medinas Bilches, Danilo; Valdés, Pamela; Osorio, Fabiola; Mercado, Gabriela; Vidal, René L.; Kerr, Bredford; Court, Felipe A.; Hetz Flores, Claudio (Public Library Science, 2015)
      ERp57 (also known as grp58 and PDIA3) is a protein disulfide isomerase that catalyzes disulfide bonds formation of glycoproteins as part of the calnexin and calreticulin cycle. ERp57 is markedly upregulated in most common ...
    • Ivorra, I.; Henriquez, M.; Lax, P.; Riquelme, G.; Morales, A. (2002)
      The materno-fetal transfer of metabolites and nutrients requires the operation of specific transport mechanisms through syncytiotrophoblast membranes. Electrophysiological studies on these cells are scarce and, because of ...
    • Alamos, Pamela; Tello, Mario; Quirós Bustamante, Paula; Gutiérrez, Fernanda; Shmaryahu, Amir; Maldonado, Juan; Levicán, Gloria; Orellana, Omar (Taylor and Francis Inc., 2018)
      © 2018, © 2018 Taylor & Francis Group, LLC. The genome of the acidophilic, bioleaching bacterium Acidithiobacillus ferrooxidans, strain ATCC 23270, contains 95 predicted tRNA genes. Thirty-six of these genes (all 20 species) ...
    • Balasubramanian, Ravikumar; Choi, Jin Ho; Francescatto, Ludmila; Willer, Jason; Horton, Edward R.; Asimacopoulos, Eleni P.; Stankovic, Konstantina M.; Plummer, Lacey; Buck, Cassandra L.; Quinton, Richard; Nebesio, Todd D.; Mericq, Verónica; Merino, Paulina M.; Meyer, (National Academy of Sciences, 2014)
      © 2014, National Academy of Sciences. All rights reserved. Inactivating mutations in chromodomain helicase DNA binding protein 7 (CHD7) cause CHARGE syndrome, a severe multiorgan system disorder of which Isolated ...