Browsing by Author "Asencio, Marcelo"

Now showing items 1-4 of 4

    • Dopaminergic pharmacology and antioxidant properties of pukateine, a natural product lead for the design ... 
      Dajas-Bailador, Federico A.; Asencio, Marcelo; Bonilla, Carolina; Scorza, Ma. Cecilia; Echeverry, Carolina; Reyes Parada, Miguel; Silveira, Rodolfo; Protais, Philippe; Russell, Graeme; Cassels Niven, Bruce; Dajas, Federico (Elsevier Science Inc., 1998-07-07)
      The dopaminergic and antioxidant properties of pukateine [(R)-11-hydroxy-1,2-methylenedioxyaporphine, PUK], a natural aporphine derivative, were analyzed in the rat central nervous system. At dopamine (DA) D1 ([3H]-SCH ...
    • Monoaminergic, Ion Channel and Enzyme Inhibitory Activities of Natural Aporphines, their Analogues and Derivatives 
      Cassels Niven, Bruce; Asencio, Marcelo (EDITORIAL BOARD, 2007-12-01)
      The aporphine alkaloids constitute the second-largest group of isoquinoline alkaloids. Nevertheless, only a relatively small number of natural aporphines and their derivatives have been studied from a pharmacological ...
    • (R)-and (S)-caclaurine from the bark of Peumus boldus 
      Asencio, Marcelo; Cassels Niven, Bruce; Speisky Cosoy, Hernán; Valenzuela Bonomo, Carlos (Elsevier, 1992-10-16)
      The Stem bark of P. boldus, in addition to the previously reported benzylisoquinoline alkaloids. sensu lato, accumulates small amounts of their common precursor (R)- aud (to a lesser extent) (S )-coclaurine.The ...
    • STRUCTURE-ANTIOXIDATIVE ACTIVITY RELATIONSHIPS IN BENZYLISOQUINOLINE ALKALOIDS 
      Cassels Niven, Bruce; Asencio, Marcelo; Conget, Paulette; Speisky Cosoy, Hernán; Videla Cabrera, Luis; Lissi Gervaso, Eduardo A. (The Italian Pharmacological Society, 1994-07-18)
      The antioxidative properties of the aporphines boldine, glaucine and apomorphine, and of the benzyltetrahydroisoquinolines (f)-coclaurine and (f)-norarmepavine were compared in the brain homogenate autoxidation model. ...