Browsing by Author "Lühr-Sierra, Susan"

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    • 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase 
      Lühr-Sierra, Susan; Vilches-Herrera, Marcelo; Fierro, Angélica; Ramsay, Rona; Edmondson, Dale E.; Reyes Parada, Miguel; Cassels Niven, Bruce; Iturriaga-Vásquez, Patricio (ELSEVIER, 2010)
      2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided ...
    • SYNTHESIS OF 2-ARYL-l,3-PROPANEDIAMlNES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE 
      Iturriaga-Vásquez, Patricio; Lühr-Sierra, Susan; Caroli Rezende, Marcos; Cassels Niven, Bruce (Sociedad Química de Chile, 2006)
      A simple synthetic route for the preparation of 2-phenyl-I,3-propanediamines, based on a Knoevenagel-Michael double .:ondensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium ...