Browsing by Author "Palma Alvarado, Verónica"

Now showing items 1-9 of 9

    • Electroporation of DNA, RNA, and morpholinos into zebrafish embryos 
      Cerda, Gustavo A.; Thomas, Jeanne E.; Allende Connelly, Miguel; Karlstrom, Rolf O.; Palma Alvarado, Verónica (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-07)
      The combination of accessible embryology and forward genetic techniques has made zebrafish a powerful model system for the study of vertebrate development. One limitation of genetic analysis is that the study of gene ...
    • Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos 
      Bergeron, Sadie A.; Milla, Luis A.; Villegas, Rosario; Shen, Meng-Chieh; Burgess, Shawn M.; Allende Connelly, Miguel; Karlstrom, Rolf O.; Palma Alvarado, Verónica (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2007-12-11)
      The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. ...
    • Molecular development of fibular reduction in birds and its evolution from dinosaurs 
      Botelhoc, Joao; Smith Paredes, Daniel; Soto Acuña, Sergio; O'Connor, Jingmai; Palma Alvarado, Verónica; Vargas Milne, Alexander (WILEY-BLACKWELL, 2016)
      Birds have a distally reduced, splinter-like fibula that is shorter than the tibia. In embryonic development, both skeletal elements start out with similar lengths. We examined molecular markers of cartilage differentiation ...
    • Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression 
      Milla Brito, Luis Apolo; Arros Villanueva, Andrea Marisol; Espinoza, Natalie; Remke, Marc; Kool, Marcel; Taylor, Michael D.; Pfister, Stefan M.; Wainwright, Brandon J.; Palma Alvarado, Verónica (UICC, 2014)
      The canonical Sonic Hedgehog (Shh)/Gli pathway plays multiples roles during central nervous system (CNS) development. To elucidate the molecular repertoire of Shh mediators, we have recently described novel transcriptional ...
    • PPAR beta/delta and PPAR gamma maintain undifferentiated phenotypes of mouse adult neural precursor cells ... 
      Bernal, Carolina; Araya, Claudia; Palma Alvarado, Verónica; Bronfman, Miguel (Frontiers Research Foundation, 2015)
      The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult mammalian brain. Stem and precursor cells in this region are the source for neurogenesis and oligodendrogesis, mainly in the olfactory ...
    • Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source 
      Martínez, Constanza; Cornejo, Víctor Hugo; Lois, Pablo; Ellis, Tammy; Solis, Natalia P.; Wainwright, Brandon J.; Palma Alvarado, Verónica (PLoS ONE, 2013)
      The Sonic Hedgehog (Shh) pathway is responsible for critical patterning events early in development and for regulating the delicate balance between proliferation and differentiation in the developing and adult vertebrate ...
    • SHh activity and localization is regulated by perlecan 
      Palma Alvarado, Verónica; Carrasco, Héctor; Reinchisi, Gisela; Olivares, Gonzalo; Faunes, Fernando; Larraín, Juan (SOC BIOLGIA CHILE, 2011)
      Proliferation and cell fate determination in the developing embryo are extrinsically regulated by multiple interactions among diverse secreted factors, such as Sonic Hedgehog (SHh), which act in a concentration-dependent ...
    • Sonic Hedgehog Stimulates Proliferation of Human Periodontal Ligament Stem Cells 
      Martínez, C.; Smith, P. C.; Rodriguez, J. P.; Palma Alvarado, Verónica (SAGE PUBLICATIONS INC, 2011-04)
      Regulation of cell renewal in the periodontium is a critical cell function that has not been clarified. Sonic hedgehog (Shh) is a secreted signaling molecule that plays a key role during development and adult tissue ...
    • Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development 
      Milla, Luis A.; Cortés, Claudio R.; Hödar Quiroga, Christian; Oñate, Maritza G.; Cambiazo Ayala, Liliana; Burgess, Shawn M.; Palma Alvarado, Verónica (BIOMED CENTRAL LTD, 2012-01-03)
      Background: The increasing number of developmental events and molecular mechanisms associated with the Hedgehog (Hh) pathway from Drosophila to vertebrates, suggest that gene regulation is crucial for diverse cellular ...