Now showing items 1-5 of 5

    • Iturriaga-Vásquez, Patricio; Zapata-Torres, Gerald; Rezende, Marcos Caroli; Cassels Niven, Bruce (2004)
      The conformational preferences of a series of 1-benzyl-1,2,3,4- tetrahydroisoquinolines (norlaudanosine and coclaurine analogues) were investigated with the aid of their 1H NMR spectra and NOESY experiments, coupled with ...
    • Zapata-Torres, Gerald; Parra-Mouchet, Julia; Cassels Niven, Bruce (1998)
      The conformational properties of ten ring-methylated N-methyl- and N,N-dimethylanilines have been studied using 13C-NMR chemical shifts and spin-lattice relaxation times in CDCl3, and semi-empirical (AM1) quantum-chemical ...
    • Bustamante, Diego; Díaz Véliz, Gabriela; Paeile Jacquier, Carlos; Zapata-Torres, Gerald; Cassels Niven, Bruce (PERGAMON-ELSEVIER SCIENCE LTD, 2004-10)
      The analgesic effects of (+)- and (-)-amphetamine (AMPH), (+/-)-p-methoxyamphetamine (MA), (+/-)-N-methyl-p-methoxyamphetamine (MMA) and (+/-)-N-ethyl-p-methoxyamphetamine (EMA) were compared using two different algesimetric ...
    • Iturriaga-Vásquez, Patricio; Carbone, Annalisa; García Beltrán, Olimpo; Livingstone, Phil D.; Biggin, Philip C.; Cassels Niven, Bruce; Wonnacott, Susan; Zapata-Torres, Gerald; Bermúdez, Isabel (The American Society for Pharmacology and Experimental Therapeutics, 2010-06-14)
      The Erythrina alkaloids erysodine and dihydro- -erythroidine (DH E) are potent and selective competitive inhibitors of 4 2 nicotinic acetylcholine receptors (nAChRs), but little is known about the molecular determinants ...
    • Scorza, Ma. Cecilia; Carrau, Cecilia; Silveira, Rodolfo; Zapata-Torres, Gerald; Cassels Niven, Bruce; Reyes Parada, Miguel (Elsevier Science Inc., 1997)
      The monoamine oxidase (MAO) inhibitory propenies of a series of amphetamine derivatives with difTerent substituents at or around rhe para position of the aromaric ring were evaluateJ. i¡, in viero stuJies in which a crude ...