Now showing items 3761-3780 of 4968

    • Faundez Parraguez, Manuel; Farias Rabelo, Nicolas; Gonzalez Gutierrez, Juan Pablo; Etcheverry Berrios, Alvaro; Alzate Morales, Jans; Adasme-Carreño, Francisco; Varas, Rodrigo; Bermúdez, Isabel; Iturriaga-Vásquez, Patricio (Elsevier, 2013)
      Nicotine is an agonist of nicotinic acetylcholine receptors (nAChRs)that has been extensively used as a template for the synthesis of a4b2-prefer ring nAChRs.Here,we used the N-methyl-pyrrolidine moiety of nicotine to ...
    • Barrientos, L.; Lang, E.; Zapata Torres, Gerald Amilcar; Celis Barros, C.; Orellana, C.; Jara Vergara, Paul; Yutronic Sáez, Nicolás (Springer, 2013)
      The structural elucidation of 2α-cyclodextrin/ 1-octanethiol, 2α-cyclodextrin/1-octylamine and 2α- cyclodextrin/1-nonanoic acid inclusion complexes by nuclear magnetic resonance (NMR) spectroscopy and molecular modeling ...
    • Bull, Alan T.; Asenjo de Leuze, Juan (Springer, 2013)
      Interests in the Atacama Desert of northern Chile until very recently were founded on its mineral resources, notably nitrate, copper, lithium and boron. Now this vast desert, the oldest and most arid on Earth, is ...
    • Marcoleta, Andrés; Marín, Macarena; Mercado, Gabriela; Valpuesta, José María; Monasterio Opazo, Octavio; Lagos Mónaco, Rosalba (American Society for Microbiology, 2013)
      Microcin E492, a channel-forming bacteriocin with the ability to form amyloid fibers, is exported as a mixture of two forms: unmodified (inactive) and posttranslationally modified at the C terminus with a salmochelin-like ...
    • Moreno, Juan Camilo; Pizarro, Lorena; Fuentes, Paulina; Handford, Michael; Cifuentes Guzmán, Víctor; Stange Klein, Claudia (PLoS ONE, 2013)
      Plant carotenoids are synthesized and accumulated in plastids through a highly regulated pathway. Lycopene b-cyclase (LCYB) is a key enzyme involved directly in the synthesis of a-carotene and b-carotene through the ...
    • Contreras Ramos, Renato; Aizman, Arie; Tapia, Ricardo A.; Cerda Monje, Andrea (American Chemical Society, 2013)
      Two complementary models of Lewis molecular acidity are introduced and tested in a wide series of 45 room temperature ionic liquids (RTIL). They are defined in the context of the conceptual density functional theory. ...
    • Cerón, María Luisa; Herrera, Bárbara; Araya Figueroa, Paulo; Gracia Caroca, Francisco; Toro Labbé, Alejandro (Springer, 2013)
      We present a theoretical study of the water gas shift reaction taking place on zirconia surfaces modeled by monoclinic and tetragonal clusters. In order to understand the charge transfer between the active species, in ...
    • Javier Campuzano, Francisco; Mateus, Marcos D.; Leitão, Paulo C.; Leitão, Pedro C.; Marín Briano, Víctor; Delgado Isasi, Luisa; Tironi, Antonio; Pierini, Jorge O.; Sampaio, Alexandra F.; Almeida, Paola; Neves, Ramiro J. (Elsevier, 2013)
      The management of coastal systems where overlapping economic interests compete for the same resources make the use of integrated approaches indispensable. The Integrated Coastal Zone Management (ICZM) focuses mainly on ...
    • Faunes, Macarena; Fernández, Sara; Gutiérrez Ibáñez, Cristián; Iwaniuk, Andrew N.; Wylie, Douglas R.; Mpodozis Marín, Jorge; Karten, Harvey J.; Marín Game, Gonzalo (Wiley Periodicals, 2013)
      The isthmic complex is part of a visual midbrain circuit thought to be involved in stimulus selection and spatial attention. In birds, this circuit is composed of the nuclei isthmi pars magnocellularis (Imc), pars ...
    • Echegaray, Eleonora; Cárdenas Valencia, Carlos; Rabi, Sandra; Rabi, Nataly; Lee, Sungmin; Zadeh, Farnaz Heidar; Toro Labbe, Alejandro; Anderson, James S.; Ayers, Paul W. (Springer, 2013)
      In our quest to explore molecules with chemically significant regions where the Fukui function is negative, we explored reactions where the frontier orbital that indicates the sites for electrophilic attack is not the ...
    • Urrutia, Pamela J.; Aguirre, Pabla; Esparza, Andrés; Tapia, Victoria; Mena, Natalia P.; Arredondo Olguín, Miguel Armando; González Billault, Christian; Núñez González, Marco (2013)
      Inflammation and iron accumulation are present in a variety of neurodegenerative diseases that include Alzheimer’s disease and Parkinson’s disease. The study of the putative association between inflammation and iron ...
    • Otero, Rodrigo A.; O’Gorman, José P. (Elsevier, 2013)
      Cervical vertebrae of elasmosaurids (Sauropterygia, Plesiosauroidea) have proven to be informative even at family level. The present paper uses a previously developed methodology based on bivariate graphic analysis that ...
    • Amigo, N.; Loyola, C.; Davis, Sergio; Gutiérrez, G. (Elsevier, 2013)
      An atomic-level simulation of the collisions between a nano-projectile against a target, both composed of copper, is presented. The study is performed by means of molecular dynamics simulations, in a system at a temperature ...
    • Ormazábal Toledo, Rodrigo; Santos, José G.; Ríos, Paulina; Castro, Enrique A.; Campodónico, Paola R.; Contreras Ramos, Renato (American Chemical Society, 2013)
      Preferential solvation in aromatic nucleophilic substitution reactions is discussed using a kinetic study complemented with quantum chemical calculations. The model system is the reaction of a series of secondary ...
    • Hojman Guiñerman, Sergio; Asenjo, Felipe A. (IOP Publishing, 2013)
      The Lagrangian equations of motion for massive spinning test particles (tops) moving on a gravitational background using general relativity are presented. The paths followed by tops are nongeodesic.An exact solution for ...
    • González Silva, Carolina; Vera, Jorge; Bono Merino, María Rosa; González Billault, Christian; Baxter, Brooke; Hansen, Anne; López, Robert; Gibson, Emily A.; Restrepo, Diego; Bacigalupo Vicuña, Juan (PLoS ONE, 2013)
      The Ca2+-activated Cl2 channel is considered a key constituent of odor transduction. Odorant binding to a specific receptor in the cilia of olfactory sensory neurons (OSNs) triggers a cAMP cascade that mediates the opening ...
    • Armas, Pablo; Margarit, Ezequiel; Mouguelar, Valeria S.; Allende Connelly, Miguel; Calcaterra, Nora B. (Plos One, 2013)
      CNBP is a nucleic acid chaperone implicated in vertebrate craniofacial development, as well as in myotonic dystrophy type 2 (DM2) and sporadic inclusion body myositis (sIBM) human muscle diseases. CNBP is highly conserved ...
    • Bostelmann Torrealba, Enrique; Le Roux, Jacobus; Vásquez, Ana; Gutiérrez, Néstor M.; Oyarzún, José Luis; Carreño, Catalina; Torres González, Teresa; Otero, Rodrigo; Llanos, Andrea; Fanning, C. Mark; Hervé Allamand, Francisco (2013)
      A succession of marine and continental strata on the southern flank of Cerro Cono in the Sierra Baguales, northeast of Torres del Paine, can be correlated with stratigraphic units exposed along the southern border of the ...
    • Banderas, Álvaro; Guiliani Guerin, Nicolás (2013)
      The biomining bacterium Acidithiobacillus ferrooxidans oxidizes sulfide ores and promotes metal solubilization. The efficiency of this process depends on the attachment of cells to surfaces, a process regulated by quorum ...
    • Bórquez Muñoz, Daniel; Olmos, Cristina; Álvarez, Sebastián; Genova, Alex Di; Maass Sepúlveda, Alejandro; González Billault, Christian (Elsevier, 2013)
      Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase predominantly active in the nervous system where it regulates several processes such as neuronal migration, cytoskeletal dynamics, axonal ...