Now showing items 1-15 of 15

    • Andrews, Mónica; Soto, Néstor; Arredondo Olguín, Miguel (Elsevier, 2015)
      Objective: The aim of this study was to determine the association between iron parameters and inflammation in obese individuals with and without type 2 diabetes mellitus (T2DM). Methods: We studied 132 obese individuals ...
    • Bravo Sagua, Roberto; Mattar, Pamela; Díaz, Ximena; Lavandero González, Sergio; Cifuentes, Mariana (Frontiers Media, 2016)
      Obesity is currently a serious worldwide public health problem, reaching pandemic levels. For decades, dietary and behavioral approaches have failed to prevent this disease from expanding, and health authorities are ...
    • D'Espessailles Tapia, Amanda; Mora, Yuly A.; Fuentes, Cecilia; Cifuentes, Mariana (Wiley, 2018)
      The study of the mechanisms that trigger inflammation in adipose tissue is key to understanding and preventing the cardiometabolic consequences of obesity. We have proposed a model where activation of the G protein-coupled ...
    • Uribarri, Jaime; Castillo, María Dolores del; Maza Cave, María Pía de la; Filip, Rosana; Gugliucci, Alejandro; Luevano Contreras, Claudia; Macias Cervantes, Maciste; Markowicz Bastos, Deborah; Medrano, Alejandra; Menini, Teresita; Portero Otin, Manuel; Rojas, Armando; Rodrigues Sampaio, Geni; Wrobel, Kazimierz; Wrobel, Katarzyna; Garay Sevilla, Eugenia (American Society for Nutrition, 2015)
      Over the past 2 decades there has been increasing evidence supporting an important contribution from food-derived advanced glycation end products (AGEs) to the body pool of AGEs and therefore increased oxidative stress ...
    • Andrews, Mónica; Soto, Néstor; Arredondo Olguín, Miguel (2012)
      Background: The pharmacological action of metformin goes beyond mere glycemic control, decreasing markers of inflammation and contributing to the reduction of oxidative stress. Aim: To evaluate biochemical, anthropometric ...
    • Rodriguez, Juan; Monsalves Álvarez, Matías; Henriquez, Sandra; Llanos Silva, Miguel; Troncoso Cotal, Rodrigo (Elsevier Science, 2016-11)
      Glucocorticoids are involved in several responses triggered by a variety of environmental and physiological stimuli. These hormones have a wide-range of regulatory effects in organisms. Synthetic glucocorticoids are ...
    • Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)
      Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
    • Andrews Guzmán, Mónica; Arredondo Olguín, Miguel Armando; Olivares Gronhert, Manuel (Aula Médica Ediciones, 2015)
      Objective: To investigate the relationship between oxidative stress and biochemical parameters and the expression of TXNIP, IL-6, IL-1 beta and TNF-alpha in peripheral mononuclear cells (PMCs) from type-2 diabetic patients. ...
    • Ormazábal, Paulina; Cifuentes, Mariana; Vari, Rosaria; Scazzocchio, Beatrice; Masella, Roberta; Pacheco Cruz, Igor; Vega, Wladimir; Paredes, Adrián; Morales, Glauco (Bentham Science, 2020)
      Background: Obesity is a major health problem associated with increased comorbiditics, which are partially triggered by inflammation. Proinflaminatory macrophage infiltration in adipose tissue of individuals with obesity ...
    • Fontvieille, Emma; His, Mathilde; Biessy, Carine; Navionis, Anne Sophie; Torres Mejías, Gabriela; Ángeles Llerenas, Angélica; Alvaro Cabrero, Isabel; Sánchez, Gloria Inés; Navarro, Edgar; Rodas Cortes, Yorlany; Porras, Carolina; Rodriguez, Ana Cecilia; Garmendia Miguel, María Luisa; Soto, José Luis; Moyano Schlegel, Leonor Agustina; Porter, Peggy L.; Lin, Ming Gang; Guenthoer, Jamie; Romieu, Isabelle; Rinaldi, Sabina (BMC, 2022)
      Background: Breast cancer incidence is increasing rapidly in Latin America, with a higher proportion of cases among young women than in developed countries. Studies have linked inflammation to breast cancer development, ...
    • Steinmaus, Craig; Castriota, Felicia; Ferreccio, Catterina; Smith, Allan H.; Yuan, Yan; Liaw, Jane; Acevedo, Johanna; Pérez, Liliana; Meza, Rodrigo; Calcagno, Sergio; Uauy Dagach-Imbarack, Ricardo; Smith, Martyn T. (Elsevier, 2015)
      Background: Elevated body mass index (BMI) is a risk factor for cardiovascular disease, diabetes, cancer, and other diseases. Inflammation or oxidative stress induced by high BMI may explain some of these effects. Millions ...
    • Reid, Brie M.; Doom, Jenalee R.; Burrows Argote, Raquel; Correa Burrows, Paulina; Lozoff, Betsy; Blanco, Estela; Gahagan, Sheila (Elsevier, 2020)
      Early adversity, depression, and obesity are associated with increases in low-grade inflammation. However, there are few prospective and longitudinal studies to elucidate how these associations unfold in children. The ...
    • Rodríguez, Juan Manuel; Leiva Balich, Laura; Concha, M. J.; Mizón, C.; Bunout Barnett, Daniel; Barrera Acevedo, Gladys; Hirsch Birn, Sandra; Jiménez Jaime, Teresa; Henríquez, Sandra; Uribarri, Jaime; Maza Cave, María Pía de la (Aula Médica Ediciones, 2015)
      Dietary intake of advanced glycation end-products (AGEs) increases circulating and tissue levels of these substances, contributing to a state of increased oxidative stress and inflammation. A low dietary AGE intervention ...
    • Andrews, Mónica; Leiva, Elba; Arredondo Olguin, Miguel Armando (Elsevier GMBH, 2016)
      Objective: We evaluated the relationship between the HO1 genotype, ferritin levels and the risk of type-2 diabetes and inflammation. Research methods: Eight hundred thirty-five individuals were evaluated and classified ...
    • Costa, Mage; Garmendia Miguel, María Luisa; Corvalán Aguilar, Camila; Reyes Jedlicki, Marcela (Mary Ann Liebert, 2016)
      Background: Overweight is associated with low-grade inflammation, but it is under debate whether the effect of fat mass accumulation is acute or chronic. We aimed to study the association of overweight duration with low-grade ...