THE PREPARATION OF POTENTIALLY PSVCHOACTIVE ~-ALKOXVPHENETHVLAMINES
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1994-10-13Metadata
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Aillón Torres, Milton
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THE PREPARATION OF POTENTIALLY PSVCHOACTIVE ~-ALKOXVPHENETHVLAMINES
Abstract
üThe preparal.1on of B-alkoxYPhenethylamlne~ 3 lS described.
As part of our ¡nteresl. in structure-actlvlty relatlonshtps of
O$'~c.hl)tomimetic phenethylamínes I ond their ínteroctíons with
serol.Onlnergic receptors 2, we describe In ttle present communlcatlon tne
preparetlOn (If a series oi substttuted ~-alkoxYPhenylethylemines.
A few of these compounds hod been prepered before 3,4 end
theír psychotropic properties described with humen volunteers, However,
ru) PMrrrll'JC')logiclIl sludies on ttlese new compoUnds heve been cerrleo out
Slnee fhen, asida from the fey.¡ instances in which 8 (i-methoxylated
derivative has shown a potency similar to or slightJy greater than that of
lhe (,orent compound
Little ís known about t.he effects of substitution at. the
!\-p(l~1tl0n (\1 tn~ Sld~ CMm of nel1uClnogeníc phenethylemiMS. elthough 1t.
.,y,jS :.peCIJleted lhet the!r ectivity might
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SYNTHETIC COMMUNICATIONS, 25(8), p. 1239-1247, 1995.
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