| Author | dc.contributor.author | Marder, Mariel | |
| Author | dc.contributor.author | Viola, Haydee | es_CL |
| Author | dc.contributor.author | Wasowski, Cristina | es_CL |
| Author | dc.contributor.author | Wolfman, Claudia | es_CL |
| Author | dc.contributor.author | Waterman, Peter G. | es_CL |
| Author | dc.contributor.author | Cassels Niven, Bruce | es_CL |
| Author | dc.contributor.author | Medina, Jorge H. | es_CL |
| Author | dc.contributor.author | Paladini, Alejandro C. | es_CL |
| Admission date | dc.date.accessioned | 2012-08-22T16:19:05Z | |
| Available date | dc.date.available | 2012-08-22T16:19:05Z | |
| Publication date | dc.date.issued | 1996-04-13 | |
| Cita de ítem | dc.identifier.citation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol. 223, p. 384-389, Article nº 0903, 1996. | es_CL |
| Identifier | dc.identifier.issn | 0006-291x | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/119556 | |
| Abstract | dc.description.abstract | 6-Bromoflavone, obtained by bromination of flavanone, binds to central benzodiazepine receptors witb a
Ki =70 nM and has a clear anxiolytic activity in mice, at 0.5 mgJkg, i.p. A survey of tbe structure/affinity relationship
for tbose receptors in a series of natural and syntbetic flavonoids is presented. | es_CL |
| Patrocinador | dc.description.sponsorship | This work has been supported by grants from Consejo Nacional de Investigaciones Científícas y Técnicas (Argentina),
Universidad de Buenos Aires (Argentina), IFS (Sweden), OAS (Washington, DC) and Fundación Antorchas (Argentina). | es_CL |
| Lenguage | dc.language.iso | en | es_CL |
| Publisher | dc.publisher | Elsevier Inc. | es_CL |
| Título | dc.title | 6-Bromoflavone, a High Affinity Ligand for the Central Benzodiazepine Receptors Is a Member of a Family of Active Flavonoids | es_CL |
| Document type | dc.type | Artículo de revista | |
