Further mulinane diterpenoids from Azorella compacta
Author
dc.contributor.author
Areche Medina, Carlos
Author
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Rojas-Álvarez, Francisca
es_CL
Author
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Campos-Briones, Carolina
es_CL
Author
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Lima, Carlos
es_CL
Author
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Pérez, Edwin G.
es_CL
Author
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Sepúlveda, Beatriz
es_CL
Admission date
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2014-01-27T14:49:50Z
Available date
dc.date.available
2014-01-27T14:49:50Z
Publication date
dc.date.issued
2013-04-11
Cita de ítem
dc.identifier.citation
Journal of Pharmacy and Pharmacology, 65, pp. 1231–1238
en_US
Identifier
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doi: 10.1111/jphp.12083
Identifier
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https://repositorio.uchile.cl/handle/2250/119706
General note
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Artículo de publicación ISI.
en_US
Abstract
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The chemical study of a dichloromethane extract from Azorella compacta
was directed to the isolation of characteristic mulinane and azorellane diterpenoids
in order to determine their gastroprotective activity.
Methods Usual chromatographic techniques on the extract led to the isolation of
12 compounds, which were identified by their spectroscopic properties. The HCl/
ethanol-induced gastric lesions model in mice was used to determine the gastroprotective
activity.
en_US
Patrocinador
dc.description.sponsorship
This work was supported by FONDECYT INICIACION
(no. 11110241), FONDECYT (no. 11090120) and ICM (no.
P10-035-F).