Determination of Nifuroxazide by Flow Injection Linear Adsorptive Stripping Voltammetry on a Screen-Printed Carbon Nanofiber Modified Electrode

Abstract

A new, sensitive, reproducible and easy-to-use flow-injection method for determining nifuroxazide based on adsorptive stripping linear sweep voltammetry over screen-printed carbon electrodes is presented. The presented method is the first report of Nifuroxazide determination using a screen printed electrode and FIA and it is useful for pharmaceutical quality control, specifically, it could be adopted as an effective portable tool for on the shelf quality control at pharmacies.Limits of quantification (LOQ) and detection (LOD) as low as 42 and 10 ng/mL, respectively, were found. An average recovery of 100.7%, and a standard deviation of 2.5 % indicates acceptable accuracy and precision validating the proposed method.