Biotransformation of ent-beyerenes with mucor plumbeus

Abstract

ABSTRACT The microbiological transformation of ent-beyer-15-en-18-ol 1 and ent-beyer-15-en-19-ol 2, using Mucor plumbeus, resulted in hydroxylated products. After nine days of incubation, 15?,16?-epoxide-ent-beyeran-7b,18-diol 3, ent-beyer-15-en-7b,19-diol 4 and 15?,16?-epoxide-ent-beyeran-7b,19-diol 5 were isolated. The metabolites were identified by spectroscopic methods.