Azorellane diterpenoids from laretia acaulis, and its toxoplasmacidal activity
| Author | dc.contributor.author | Loyola, Luis A. | |
| Author | dc.contributor.author | Borquez, Jorge | |
| Author | dc.contributor.author | Morales, Glauco | |
| Author | dc.contributor.author | Araya, Jorge | |
| Author | dc.contributor.author | Gonzalez, Jorge | |
| Author | dc.contributor.author | Neira, Ivan | |
| Author | dc.contributor.author | Sagua, Hern A.N. | |
| Author | dc.contributor.author | San Martín Barrientos, Aurelio | |
| Admission date | dc.date.accessioned | 2018-12-20T14:35:57Z | |
| Available date | dc.date.available | 2018-12-20T14:35:57Z | |
| Publication date | dc.date.issued | 2001 | |
| Cita de ítem | dc.identifier.citation | Boletin de la Sociedad Chilena de Quimica, Volumen 46, Issue 1, 2018, Pages 009-013 | |
| Identifier | dc.identifier.issn | 03661644 | |
| Identifier | dc.identifier.other | 10.4067/S0366-16442001000100003 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/156632 | |
| Abstract | dc.description.abstract | In addition to azorellanol a new diterpenoid 7-deacetylazorellanol, has been isolated from the aerial parts oiLaretia acaulis (Cav.) Gill et Hook (Umbelliferae). Its structure was based on spectroscopic comparison with azorellanol and chemical grounds. Azorellanol and 7-deacetylazorellanol showed marked inhibitor activity against trophozoites of protozoan parasite Toxoplasma gondii. The 50 % inhibitory dose for azorellanol was calculated in 54 nM and for 7-deacetylazorellanol was 42 nM. | |
| Lenguage | dc.language.iso | en | |
| Publisher | dc.publisher | Sociedad Chilena de Quimica | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Boletin de la Sociedad Chilena de Quimica | |
| Keywords | dc.subject | 7-deacetylazorellanol | |
| Keywords | dc.subject | Azorellanol | |
| Keywords | dc.subject | Diterpenoids | |
| Keywords | dc.subject | Laretia acaulis | |
| Keywords | dc.subject | Toxoplasma gondii | |
| Título | dc.title | Azorellane diterpenoids from laretia acaulis, and its toxoplasmacidal activity | |
| Document type | dc.type | Artículo de revista | |
| dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile