Costunolide and Flavonols from Gochnatia Foliosa Var. Fascicularis

Abstract

As part of a systematic chemical investigation of Chilean Compositae (1-3), we examined the secondar chemistry of a member of the genus Gochnatia (tribe Mutisieae, subtribe Gochnatiinae): Gochnatia foliosa var. fscicularia (Don) Cabrera. Stems and leaves yielded a germacrane-type lactone, costunolide, and four flavonoids: 3,7-dimethylkaempferol, 3,3'-dimethylquercetin, 3'-methvlquercetin, and 3,7-dimethylquercetin. Five other members of the South American genus have been chemically analyzed (4, 5). A flavonol and costunolide have also been reported from Gochnatiapaniculata (5). © 1984, American Chemical Society. All rights reserved.