Cholinergic transmission in vas deferens

Abstract

1. 1. Prazosin, haloperidol, propranolol or timolol had no effect on the electrically evoked muscular twitch. 2. 2. Atropine was able to antagonize competitively acetylcholine (pA2 = 9.29 ± 0.30). 3. 3. The muscular twitch of the Octodon degus vas deferens was only partially abolished by atropine (53.2 ± 0.72). 4. 4. The present results can be interpreted assuming that the Octodon degus vas deferens has one component muscarinic in its innervation. © 1983.