Starvation effect on rat kidney peroxisomal and microsomal fatty acid oxidation. A comparative study between liver and kidney
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Orellana, Myriam
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Starvation effect on rat kidney peroxisomal and microsomal fatty acid oxidation. A comparative study between liver and kidney
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Microsomal lauric acid 12-hydroxy lauric acid (ω)-hydroxylation and fatty acid peroxisomal β-oxidation were studied in kidney tissue from starved rats. Starvation increased the microsomal ω-hydroxylation and peroxisomal β-oxidation of fatty acids with a high correlation between both processes. Earlier, we reported similar results in liver. Our results support the hypothesis that the role of microsomal fatty acids ω-hydroxylation is the generation of substrate for peroxisomal β-oxidation, with the final purpose of contributing to a catabolic or gluconeogenic pathway from fatty acids. © 1993.
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URI: https://repositorio.uchile.cl/handle/2250/157968
DOI: 10.1016/0014-5793(93)81111-C
ISSN: 00145793
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FEBS Letters, Volumen 322, Issue 1, 2018, Pages 61-64
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