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Cerebral oxygen uptake (vo2cer) decreases during acute hypoxemia in the llama fetus

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1997
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Riquelme, Ronald
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Cerebral oxygen uptake (vo2cer) decreases during acute hypoxemia in the llama fetus
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Author
  • Riquelme, Ronald;
  • Moraga, Fernando;
  • Cabello, Gertrudis;
  • Llanos Mansilla, Jorge;
Abstract
Cerebral blood flow (CBF) in the llama fetus does not augment during acute hypoxemia, decreasing cerebral oxygen delivery. To investigate whether VO2 cer could be maintained during hypoxemia by increasing cerebral oxygen extraction, we placed catheters in ascending and descending aorta, inferior vena cava and sagital sinus in 7 llama fetuses (0.6-0.7 of gestation). At 4th days post-surgery, measurements were made of hemoglobin saturation, carotid (Ca O2) and sagital (CsO2) oxygen content, CBF (radiolabelled micropheres) basally and after 60 min of hypoxemia) (15% Hb sat in ascending aorta). Results: means ± SEM; *p<0.05 Basal vs. Hypoxemia.
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Identifier
URI: https://repositorio.uchile.cl/handle/2250/159816
DOI: 10.1203/00006450-199701000-00049
ISSN: 15300447
00313998
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Pediatric Research, Volumen 41, Issue 1, 1997,
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