DNA methylation in Trypanosoma cruzi
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1990Abstract
DNA isolated from the protozoan Trypanosoma cruzi has been found to contain 5-methylcytosine. Analysis of T. cruzi DNA by both HpaII and MspI restriction endonucleases suggests that the sequence -CCGG- is not methylated. Probably T. cruzi DNA also contains N6-methyladenine. This report constitutes the first clear demonstration of the presence of methylated bases in the nuclear DNA from trypanosomes.
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Artículo de publicación SCOPUS
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URI: https://repositorio.uchile.cl/handle/2250/160046
DOI: 10.1016/0014-5793(90)80717-W
ISSN: 00145793
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FEBS Letters, Volumen 263, Issue 1, 1990, Pages 113-116
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