Browsing by Author "2c5263a2-2a5b-4bf9-99e9-300e53350dd9"

Now showing items 1-3 of 3

    • Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro 
      Ocaranza, Maria Paz; Lavandero González, Sergio; Jalil Milad, Jorge; Moya, Jaqueline; Pinto, Melissa; Novoa, Ulises; Apablaza, Felipe; González, Leticia; Hernández, Carol; Varas, Manuel; López, René; Godoy, Iván; Verdejo, Hugo; Chiong Lay, Mario (Lippincott Williams and Wilkins, 2010)
      Background: Angiotensin-(1-9) is present in human and rat plasma and its circulating levels increased early after myocardial infarction or in animals treated with angiotensin-converting enzyme inhibitor. However, the ...
    • Changes in cyclic AMP dependent protein kinase and active stiffness in the rat volume overload model of ... 
      Lavandero González, Sergio; Cartagena, Gastón; Guarda, Eduardo; Corbalán, Ramón; Godoy, Iván; Sapag Hagar, Mario; Jalil Milad, Jorge (Oxford University Press, 1993)
      Objective: The aim was to clarify the role of cyclic AMP dependent protein kinase (PKA) and changes in mechanical heart function during development of cardiac hypertrophy induced by volume overload. Methods: Protein and ...
    • Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2 
      Ocaranza, María Paz; Valderas, Patricio; Moya, Jackeline; Gabrielli, Luigi; Godoy, Iván; Córdava, Samuel; Mac Nab, Paul; García Nannig, Lorena; Farías, Luis; Jalil, Jorge E. (BMC, 2020)
      BackgroundThe intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ...