Browsing by Author "f3726e28-e8ba-494d-bf27-4a035ef56333"

Now showing items 21-23 of 23

    • Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease 
      Bravo Sagua, Roberto; Parra Ortiz, Valentina; Muñoz Córdova, Felipe; Sánchez Aguilera, Pablo; Garrido, Valeria; Contreras Ferrat, Ariel; Chiong Lay, Mario; Lavandero González, Sergio (Elsevier, 2020)
      The sarco/endoplasmic reticulum is an extensive, dynamic and heterogeneous membranous network that fulfills multiple homeostatic functions. Among them, it compartmentalizes, stores and releases calcium within the intracellular ...
    • The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content 
      Shaikh, S.; Troncoso Cotal, Rodrigo; Mondaca Ruff, David; Parra Ortíz, María Valentina; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio (Elsevier, 2018)
      Stromal-interaction molecule 1 (STIM1)-mediated store-operated Ca2+ entry (SOCE) plays a key role in mediating cardiomyocyte hypertrophy, both in vitro and in vivo. Moreover, there is growing support for the contribution ...
    • TonEBP suppresses IL-10-mediated immunomodulation 
      Choi, Soo Youn; Hee Lee, Hwan; Lee, Jun Ho; Ye, Byeong Jin; Yoo, Eun Jin; Kang, Hyun Je; Jung, Gyu Won; An, Seung Min; Lee-Kwon, Whaseon; Chiong Lay, Mario; Lavandero González, Sergio; Kwon, Hyug Moo (Nature, 2016)
      TonEBP is a key transcriptional activator of M1 phenotype in macrophage, and its high expression is associated with many inflammatory diseases. During the progression of the inflammatory responses, the M1 to M2 phenotypic ...