Browsing by Author "Jalil Milad, Jorge"
Now showing items 1-20 of 25
-
(Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2000)El objetivo del estudio fue estimar la prevalencia de los distintos alelos del polimorfismo del gen de la enzima convertidora de angiotensina (ECA), inserción/deserción (I/D) y simultáneamente la actividad de ECA plasmática ...
-
(LIPPINCOTT WILLIAMS & WILKINS, 2002-03)Background and objective In humans, the insertion/ deletion polymorphism in the anglotensin (Ang) I converting enzyme (ACE) gene significantly determines ACE activity. The deletion allele induces higher ACE levels and is ...
-
(International Medical Science for Experimental and Clinical Research, 2002)The insertion/delection ACE polymorphism (ACE I/D) regulates different levels of circulating and tissue ACE activities, which may induce diverse adrenergic responses to physiological stimuli. The aim of this study was ...
-
(LIPPINCOTT WILLIAMS & WILKINS, 2001-09)Angiotensin I is a substrate for both ACE and for neutral endopeptidase 24.11 (NEP). We hypothesized that high ACE expression is related to low NEP activity. Accordingly, circulating and tissue NEP and ACE activities were ...
-
(Lippincott Williams and Wilkins, 2014)BACKGROUND:: Little is known about the biological effects of angiotensin-(1-9), but available evidence shows that angiotensin-(1-9) has beneficial effects in preventing/ameliorating cardiovascular remodeling. OBJECTIVE:: ...
-
(EDICIONES DOYMA S/L, 2001-11)Introduction. Angiotensin II levels can be partially inhibited during chronic administration of angiotensin converting enzyme (ACE) inhibitors, limiting from a clinical point of view its efficacy in the treatment of ...
-
(PERGAMON-ELSEVIER SCIENCE LTD, 2006-02-28)To determine circulating angiotensin-(1-7) [Ang-(1,7)] levels in rats with different angiotensin converting enzyme (ACE) genotypes and to evaluate the effect of hypertension on levels of this heptapeptide, plasma levels ...
-
(PERGAMON-ELSEVIER SCIENCE LTD, 1999-03-26)There is some evidence that cardiac rather than circulating insulin-like growth factor-1 (IGF-1) levels contribute to the development of renovascular hypertensive left ventricular hypertrophy (LVH), remaining unknown the ...
-
(LIPPINCOTT WILLIAMS & WILKINS, 2005-12)In humans and rats, angiotensin I-converting enzyme activity is significantly determined by a gene polymorphism. Homozygous Brown Norway rats have higher plasma angiotensin I-converting enzyme activity and circulating ...
-
(LIPPINCOTT WILLIAMS & WILKINS, 2002-08)This study investigated whether long-term administration of isoproterenol (ISO) induces differential expression of angiotensin-converting enzyme (ACE) in lung, plasma, and left ventricle (LV) during development of left ...
-
(EXCERPTA MEDICA INC, 2003-09-15)In patients with hypertension who have the DD-ACE genotype (higher angiotensin-converting enzyme [ACE] activity), plasma levels of angiotensin-(1-7) are 4 times lower than in patients with the II-ACE genotype (lower ACE ...
-
(Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2003)La mayor actividad de la enzima convertidora de angiotensina I (ECA) determina mayores niveles de angiotensina (Ang) II y menores de Ang-(1-7). Hemos observado mayores niveles de Ang II en ratas normotensas con mayor ...
-
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008-07-25)Changes in cardiac osmolarity occur in myocardial infarction. Osmoregulatory mechanisms may, therefore, play a crucial role in cardiomyocyte survival. Tonicity-responsive enhancer binding protein (TonEBP) is a key ...
-
(Universidad de Chile, 2009)TonEBP, la proteína que se une al elemento regulatorio que responde a tonicidad “TonE” es el único factor transcripcional conocido de eucariontes que responde a cambios de la osmolaridad extracelular. Este factor transcripcional ...
-
(LIPPINCOTT WILLIAMS & WILKINS, 2005-09)Administration of the P-adrenergic agonist isoproterenol results in cardiac apoptosis. The effect of short-term P-adrenergic stimulation by isoproterenol on the activity of plasma, lung, and left ventricular (LV) angiotensin ...
-
(EDICIONES DOYMA S/L, 2002-08)Introduction and objective. Chronic heart failure (CHF) is associated with oxidative stress. Heart transplantation, an important therapeutic alternative in these patients, could reduce oxidative stress by improving cardiac ...
-
(Sociedad Chilena de Cardilología y Cirugía Cardiovascular, 2005)Los polimorfismos de los receptores β Adrenérgicos (AR) influencian el grado de actividad del receptor. Los βAR tienen un rol importante en la regulación de la contractilidad y podrían tener implicancias en el riesgo de ...
-
Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats (AMER PHYSIOLOGICAL SOC, 2004-02-01)In humans, the effect of angiotensin-converting enzyme (ACE) gene polymorphisms in cardiovascular disease is still controversial. In the rat, a microsatellite marker in the ACE gene allows differentiation of the ACE gene ...
-
(ELSEVIER SCIENCE INC, 1999-07)The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...
-
(Sociedad Española de Cardiología, 2001)En este modelo experimental de HVI hipertensiva mixta existe una activación temprana de la ECA plasmática y cardíaca. La administración precoz de un IECA previene el desarrollo de hipertensión e HVI al inhibir el aumento ...
