Browsing by Title Artículos de revistas

Now showing items 1315-1334 of 2801

    • The IKK complex contributes to the induction of autophagy 
      Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Helene; Maiuri, M. C.; Morselli, E.; Vitale, I.; Kepp, O.; Tasdemir, E.; Galluzzi, Lorenzo; Shen, S.; Tailler, M.; Delahaye, N.; Tesniere, A.; De Stefano, D.; Ben Younes, Amena; Harper, F.; Pierron, G.; Lavandero González, Sergio; Zitvogel, L.; Israel, A; Baud, V; Kroemer, Guido (NATURE PUBLISHING GROUP, 2010-02-03)
      In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient depletion, trigger the ...
    • IKK connects autophagy to major stress pathways 
      Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Hélène; Maiuri, Maria Chiara; Morselli, Eugenia; Vitale, Ilio; Kepp, Oliver; Tasdemir, Ezgi; Galluzzi, Lorenzo; Shen, Si; Tailler, Maximilien; Delahaye, Nicolas; Tesniere, Antoine; De Stefano, Daniela; Younes, Aména Ben; Harp (Taylor and Francis Inc., 2010)
      Cells respond to stress by activating cytoplasmic mechanisms as well as transcriptional programs that can lead to adaptation or death. Autophagy represents an important cytoprotective response that is regulated by both ...
    • Immobilization of graphene-derived materials at gold surfaces: Towards a rational design of protein-based ... 
      Primo, Emiliano N.; Bollo Dragnic, Soledad; Rubianes, María D.; Rivas, Gustavo A. (Pergamon-Elsevier Science LTD, 2018)
      This work is focused on the critical analysis of the non-covalent modification of a thiolated-gold surface with different grapheneous materials and the covalent attachment of bovine serum albumin (BSA) as a model protein. ...
    • Immobilization of rhodamine 6G in calcium alginate microcapsules based on aromatic-aromatic interactions ... 
      Araya Hermosilla, Esteban; Muñoz, Daniel; Orellana, Sandra; Yáñez, Alejandro; Olea, Andrés F.; Oyarzún Ampuero, Felipe; Moreno Villoslada, Ignacio (Elsevier, 2014)
      Immobilization of rhodamine 6G in calcium alginate microcapsules was achieved using the polyanion bearing negatively charged aromatic groups poly(sodium 4-styrenesulfonate) as complexing agent. The immobilization of the ...
    • Immobilized enzyme reactors. Diffusion/convection, kinetics, and a comparison of packed-column and rotating ... 
      López Ruiz, Beatríz; Sánchez Cabezudo, M.; Richter Duk, Pablo; Mottola, H. A. (AMER CHEMICAL SOC, 1996-05-15)
      The roles of chemical kinetics and mass transfer in two types of bioreactors (packed-column reactors and rotating disk bioreactors), used with continuous-now sample/reagent(s) processing, are discussed in detail. A normalized ...
    • The Impact of a Carbon Tax on the Chilean Electricity Generation Sector 
      Benavides Farías, Carlos; Gonzales, Luis; Díaz Romero, Manuel; Fuentes, Rodrigo; García, Gonzalo; Palma Behnke, Rodrigo; Ravizza, Catalina (MDPI, 2015)
      This paper aims to analyse the economy-wide implications of a carbon tax applied on the Chilean electricity generation sector. In order to analyse the macroeconomic impacts, both an energy sectorial model and a Dynamic ...
    • Impact of the simulated gastric digestion methodology on the In vitro intestinal proteolysis and lipolysis ... 
      Mella Caro, Camila; Quilaqueo, Michelle; Zúñiga, Rommy N.; Troncoso, Elizabeth (MDPI, 2021)
      The aim of this work was to study the impact of the methodology of in vitro gastric digestion (i.e., in terms of motility exerted and presence of gastric emptying) and gel structure on the degree of intestinal proteolysis ...
    • Importance of the electrolyte cation on the non-covalent interactions in the electrooxidation of 1-heptanol ... 
      Ureta Zañartú, María Soledad; Méndez Torres, Ana María; Fernández, Francisco; Ilabaca, Jacqueline; Mascayano, Carolina; Gutiérrez, Claudio (Elsevier, 2020)
      In order to determine the possible non-covalent influence of the alkali metal cation on the electrooxidation of 1-heptanol on gold in alkali metal hydroxides, 0.1 M MOH solutions, where M = Li, Na, K, Rb, and Cs, have been ...
    • Importancia de la biorregulación celular en la patología humana 
      Sapag Hagar, Mario (Universidad de chile, 1985)
    • Importancia de la protección de la materia orgánica en suelos 
      Aguilera S., S. María (Sociedad Chilena de la Ciencia del Suelo, 2000)
      Entre los principales intereses mundiales hoy se tiene la gran conciencia del resguardo y recuperación de nuestros principales recursos naturales, entre los cuales es fundamental el sistema edáfico. Los suelos, con fines ...
    • Improved selective reduction of 3-formylchromones using basic alumina and 2-propanol 
      Araya Maturana, Ramiro; Heredia Moya, Jorge; Pessoa Mahana, Hernán; Weiss López, Boris (MARCEL DEKKER INC, 2003)
      Treatment of formylchromones, dissolved in 2-propanol with basic alumina at 75degreesC, selectively reduces the formyl group with good yields without any activation process of the alumina.
    • Improved stability of multicopper oxidase carbon nanotube conjugates using a thermophilic laccase 
      Atalah Zúñiga, Joaquín Ignacio; Zhou, Yan; Espina, Giannina; Blamey, Jenny M.; Ramasamy, Ramaraja P. (Royal Society of Chemistry, 2018)
      A recombinant laccase from thermophilic bacteria was used to construct an enzyme-multi-walled carbon nanotube composite catalyst, which shows improved stability as a bio-electrocatalyst for the oxygen reduction reaction ...
    • Improvement in the oral bioavailability and efficacy of new ezetimibe formulations—comparative study of a ... 
      Torrado Salmerón, Carlos; Guarnizo Herrero, Víctor; Gallego Arranz, Teresa; Val-Sabugo, Yvonne del; Torrado, Guillermo; Morales Valenzuela, Javier; Torrado Santiago, Santiago (MDPI, 2020)
      Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the ...
    • Improvement of galangin solubility using native and derivative cyclodextrins. An UV-Vis and NMR study 
      Jullian Matthaei, Carolina (2009)
      The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydroxypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ...
    • Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide 
      Riveros Salvatierra, Ana; Eggeling, Cynthia; Riquelme Barrios, Sebastián; Adura, Carolina; López Iglesias, Carmen; Guzmán, Fanny; Araya Fuentes, Eyleen; Almada, Mario; Juárez, Josue; Valdez, Miguel A.; Fuentevilla Morgado, Ignacio; López, Olga; Kogan Bocian, Marcelo (Dove Medical Press, 2020)
      Introduction: Gold nanorods are highly reactive, have a large surface-to-volume ratio, and can be functionalized with biomolecules. Gold nanorods can absorb infrared electromagnetic radiation, which is subsequently dispersed ...
    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide 
      Guerrero, Simon; Araya, Eyleen; Fiedler Temer, Jenny; Arias, J.; Adura, Carolina; Albericio, Fernando; Giralt, Ernest; Arias, José; Fernández, María Soledad; Kogan Bocian, Marcelo (2010)
      Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...
    • In situ Electroreduction of Graphene Oxide: Increased Sensitivity for the Determination of NADH 
      Báez, Daniela F.; Tapia, Felipe; Sierra Rosales, Paulina; Bollo Dragnic, Soledad (Wiley-VCH Verlag, 2019)
      A novel and useful method to catalyze the electro-oxidation of nicotinamide adenine dinucleotide (NADH) over a glassy carbon electrode (GCE) modified with graphene oxide (GO) is presented. Based on the presence of oxygen ...
    • In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl ... 
      Aguirre, G.; Boiani, Lucía; Cerecetto, Hugo; Fernández, M.; González, M.; Denicola, Ana; Otero, L.; Gambino, Dinorah; Rigol Olsen, Carolina; Olea Azar, Claudio; Faúndez Cáceres, Mario Antonio (PERGAMON-ELSEVIER SCIENCE LTD, 2004-09-15)
      The in vitro growth inhibition activity of new thiosemicarbazone derivatives against the protozoan parasite Trypanosoma cruzi, the causative agent of American trypanosomiasis, are described. The designed compounds combine ...
    • In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles 
      Boiani, Lucia; Gerpe, Alejandra; Arán, Vicente; Torres de Ortiz, Susana; Serna, Elva; Vera de Bilbao, Ninfa; Sanabria, Luis; Yaluff, Gloria; Nakayama, Héctor; Rojas de Arias, Antonieta; Maya Arango, Juan; Morello, J.; Cerecetto, Hugo; González, Mercedes (2009)
      Previously, we have identified a series of 5-nitroindazoles with good antiprotozoal activities, against Trypanosoma cruzi epimastigotes and Trichomonas vaginalis. Most of them have shown very low unspecific toxicity on ...