Browsing by Subject "Devimistat"

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    • FRI-1 is an anti-cancer isoquinolinequinone that inhibits the mitochondrial bioenergetics and blocks metabolic ... 
      Córdova Delgado, Miguel Angel; Fuentes Retamal, Sebastián Andrés; Palominos, Charlotte; López Torres, Camila Alejandra; Guzmán Rivera, Daniela; Ramírez Rodríguez, Oney; Araya Maturana, Ramiro; Urra Faúndez, Félix Ariel (MDPI, 2021)
      Since breast cancer (BC) cells are dependent on mitochondrial bioenergetics for promoting proliferation, survival, and metastasis, mitochondria highlight as an important target for anticancer drug discovery. FRI-1, methyl ...