Browsing by Subject "Essential hypertension"

Now showing items 1-7 of 7

    • 11β-hydroxysteroid dehydrogenase type-2 and type-1 (11β-HSD2 and 11β-HSD1) and 5β-reductase activities in ... 
      Campino, Carmen; Carvajal, Cristian A.; Cornejo, Javiera; San Martín Núñez, Betty; Olivieri, Oliviero; Guidi, Giancesare; Faccini, Giovanni; Pasini, Francesco; Sateler, Javiera; Baudrand, Rene; Mosso, Lorena; Owen, Gareth I.; Kalergis, Alexis M.; Padilla, Oslando; Fardella, Patricia (2010)
      Cortisol availability is modulated by several enzymes: 11β-HSD2, which transforms cortisol (F) to cortisone (E) and 11β-HSD1 which predominantly converts inactive E to active F. Additionally, the A-ring reductases (5α- and ...
    • A comparison of the effects of the selective peripheral α1-blocker terazosin with the selective β1-blocker ... 
      Ligueros, M.; Unwin, R.; Wilkins, M. R.; Humphreys, J.; Coles, S. J.; Cleland, J. (Springer-Verlag, 1992)
      The effects of six weeks of treatment with the selective peripheral α1-adrenoceptor blocker terazosin, or the selective β1-adrenoceptor blocker atenolol on blood pressure, exercise performance and blood lipid profile were ...
    • The Expression of RAC1 and Mineralocorticoid Pathway- Dependent Genes are Associated With Different Responses ... 
      Tapia Castillo, Alejandra; Carvajal, Cristian; Campino, Carmen; Hill, Caroline; Allende, Fidel; Vecchiola, Andrea; Carrasco, Carmen; Bancalari, Rodrigo; Valdivia, Carolina; Lagos, Carlos; Martínez Aguayo, Alejandro; García, Hernán; Aglony, Marlene; Baudrand, René; Kalergis, Alexis; Michea Acevedo, Luis; Riedel, Claudia; Fardella, Carlos (Oxford University Press, 2015)
      BACKGROUND Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) activity. Rac1 could affect the expression of oxidative stress markers, such as ...
    • Modulation of (Na,K)-ATPase activity by membrane fatty acid composition: Therapeutic implications in human ... 
      Rodrigo Salinas, Ramón; Miranda-Merchak, Andres; Grau, Rodrigo Valenzuela; Bachler, Juan P.; Vergara, Leonardo (2014)
      Oxidative stress (OS) plays a key role in the pathophysiology of essential hypertension and is associated with changes in the cell membrane fatty acid composition and fluidity. As (Na,K)-ATPase is modulated by the surrounding ...
    • Relationship between (Na + K)-ATPase activity, lipid peroxidation and fatty acid profile in erythrocytes ... 
      Rodrigo Salinas, Ramón; Bächler, Jean P.; Araya, Julia; Prat Martorell, Hernán; Passalacqua Rivanera, Walter (2007)
      Oxidative stress may play a role in the pathogenic mechanism of essential hypertension. Lipid peroxidation can alter the cellular structure of membrane-bound enzymes by changing the membrane phospholipids fatty acids ...
    • Relationship between oxidative stress and essential hypertension 
      Rodrigo Salinas, Ramón; Prat Martorell, Hernán; Passalacqua Rivanera, Walter; Araya, Julia; Guichard, Cristián; Bächler, Jean P. (2007)
      This study investigated the association of blood pressure with blood oxidative stress-related parameters in normotensive and hypertensive subjects. A cross-sectional design was applied to 31 hypertensive patients and 35 ...
    • The expression of RAC1 and mineralocorticoid pathway-dependent genes are associated with different responses ... 
      Tapia Castillo, Alejandra; Carvajal, Cristian A.; Campino, Carmen; Hill, Caroline; Allende, Fidel; Vecchiola, Andrea; Carrasco, Carmen; Bancalari, Rodrigo; Valdivia, Carolina; Lagos, Carlos; Martínez Aguayo, Alejandro; Garcia, Hernan; Aglony, Marlene; Baudrand, Rene F (Oxford University Press, 2015)
      © American Journal of Hypertension, Ltd 2014. All rights reserved.Background Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) activity. Rac1 could affect ...