Browsing by Subject "ROS"

Now showing items 1-4 of 4

    • c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human ... 
      Tobar, Nicola´s; Toyos, Marcela; Urra, Carla; Me´ndez, Nicola´s; Arancibia, Rodrigo; Smith, Patricio C.; Marti´nez, Jorge (BioMed Central Ltd., 2014)
      © 2014 Tobar et al.; licensee BioMed Central Ltd. Background: Hard consistency, developed under the influence of tumor cell factors, is a characteristic feature of a breast tumor. Activation of resident fibroblasts leading ...
    • Comparative effects of superoxide anion and hydrogen peroxide on microsomal and cytosolic glutathione ... 
      Letelier, María Eugenia; Molina Berríos, Alfredo Enrique; Cortés-Troncoso, Juan; Jara Sandoval, José; Müller, Andrea; Aracena Parks, Paula (2010)
      Glutathione S-transferases (GSTs) are isoenzymes occurring in the cytoplasm and as integral membrane proteins. In addition to their role in drug metabolism by conjugating electrophilic and lipophilic compounds with glutathione ...
    • Mitochondria and calcium regulation as basis of neurodegeneration associated with aging 
      Müller, Marioly; Ahumada-Castro, Ulises; Sanhueza, Mario; González Billault, Christian; Court, Felipe A.; Cárdenas, César (Frontiers Media S.A., 2018)
      © 2018 Müller, Ahumada-Castro, Sanhueza, Gonzalez-Billault, Court and Cárdenas.Age is the main risk factor for the onset of neurodegenerative diseases. A decline of mitochondrial function has been observed in several ...
    • The use of antioxidants as potential co-adjuvants to treat chronic chagas disease 
      Maldonado Maldonado, Edio Luis; Rojas, Diego; Urbina, Fabiola; Solari Illescas, Aldo Gerónimo (MDPI, 2021)
      Chagas disease is a neglected tropical disease caused by the flagellated protozoa Trypanosome cruzi. This illness affects to almost 8-12 million people worldwide, however, is endemic to Latin American countries. It is ...