Now showing items 1-3 of 3

    • A novel caveolin-1/p85α/Rab5/Tiam1/Rac1 signaling axis in tumor cell migration and invasion 

      Díaz, Jorge; Mendoza, Pablo; Silva, Patricio; Quest, Andrew F. G.; Torres, Vicente A. (Landes Bioscience, 2014)
      © Jorge Díaz, Pablo endoza, Patricio Silva, Andrew FG Quest, and Vicente A Torres. The small GTPase Rab5 has been frequently studied in the context of intracellular trafficking, but evidence obtained more recently has ...
    • Crosstalk between Rac1-mediated actin regulation and ROS production 

      Acevedo, Alejandro; González Billault, Christian (Elsevier Inc., 2018)
      © 2018 Elsevier Inc.The small RhoGTPase Rac1 is implicated in a variety of events related to actin cytoskeleton rearrangement. Remarkably, another event that is completely different from those related to actin regulation ...
    • Rab5 is required in metastatic cancer cells for caveolin-1-enhanced Rac1 activation, migration and invasion 

      Díaz, Jorge; Mendoza, Pablo; Ortiz, Rina; Díaz, Natalia; Leyton Campos, Lisette; Stupack, Dwayne; Quest, Andrew F. G.; Torres, Vicente A. (Company of Biologists Ltd, 2014)
      Rab5 is a small GTPase that regulates early endosome trafficking and other cellular processes, including cell adhesion and migration. Specifically, Rab5 promotes Rac1 activation and cancer cell migration, but little is ...