Browsing by Subject "Redox modifications"

Now showing items 1-2 of 2

    • High fat diet induced obesity produces spontaneous ventricular arrhythmias and increases the activity of ... 
      Sánchez, Gina; Araneda, Felipe; Peña, Juan Pedro; Finkelstein, José Pablo; Riquelme, Jaime A.; Montecinos, Luis; Barrientos Briones, Genaro; Llanos Vidal, Paola; Pedrozo Cibils, Zully; Said, Matilde; Bull Simpfendorfer, Ricardo; Donoso Laurent, Paulina (MDPI, 2018)
      Ventricular arrhythmias are a common cause of sudden cardiac death, and their occurrence is higher in obese subjects. Abnormal gating of ryanodine receptors (RyR2), the calcium release channels of the sarcoplasmic reticulum, ...
    • Reversible redox modifications of ryanodine receptor ameliorate ventricular arrhythmias in the ischemic-reperfused ... 
      Becerra, Romina; Román, Bárbara; Di Carlo, Mariano; Mariangelo, Juan Ignacio; Salas, Margarita; Sánchez, Gina; Donoso Laurent, Paulina; Schinella, Guillermo; Vittone, Leticia; Wehrens, Xander; Mundiña Weilenmann, Cecilia; Said, Matilde (American Physiological Society, 2016)
      Previous results from our laboratory showed that phosphorylation of ryanodine receptor 2 (RyR2) by Ca2+ calmodulin-dependent kinase II (CaMKII) was a critical but not the unique event responsible for the production of ...