Browsing by Subject "Tacrolimus"

Now showing items 1-5 of 5

    • CYP3A5 and UGT1A9 polymorphisms influence immunosuppressive therapy in pediatric kidney transplant recipients 
      Krall Opazo, Paola; Yáñez, Dominique; Rojo, Angélica; Delucchi Bicocchi, María Angela; Córdova, Miguel; Morales, Jorge; Boza, Pía; Rivera, Alonso de la; Espinoza, Natalie; Armijo, Natalia; Castañeda, Luis E.; Farfán Urzúa, Mauricio; Salas, Carolina (Frontiers Media, 2021)
      Background: Tacrolimus (TAC) and mycophenolic acid (MPA) are the main immunosuppressive drugs used in pediatric kidney transplantation. Single nucleotide polymorphisms (SNPs) in metabolizing enzymes and transporters might ...
    • Early steroid withdrawal in pediatric renal transplantation Retiro precoz de esteroides en la inmunosupresión ... 
      Delucchi Bicocchi, María Angela; Valenzuela A, Marcela; Ferrario B, Mario; Lillo D, Ana María; Guerrero G, José Luis; Rodríguez S, Eugenio; Cano Schuffeneger, Francisco; Cavada Chacón, Gabriel; Godoy L, Jorge; Rodríguez H, Jorge; González G, Gloria; Buckel B, Erwin; Contreras M, Luis (2006)
      Background: Cardiovascular risk, growth failure and the new immunosuppressive drugs, have encouraged steroid withdrawal or total avoidance with promising results in renal transplant (Tx) immunosuppression. Aim: To evaluate ...
    • Effect of CYP3A4, CYP3A5, MDR1 and POR genetic polymorphisms in immunosuppressive treatment in chilean ... 
      Contreras Castillo, Stephania Nichols; Plaza, Anita; Stojanova, Jana; Navarro, Gustavo; Carmona, Rodolfo; Corvalán, Fernando; Cerpa, Leslie; Sandoval, Christopher; Muñoz, Daniel; Leiva, Marina; Castañeda Sepúlveda, Luis Eduardo; Farías, Nayaret; Álvarez, Carolina; Llull Morchio, Gabriel Eduardo; Mezzano, Sergio; Ardiles, Leopoldo; Varela Figueroa, Nelson Miguel; Rodríguez, María S.; Flores, Claudio; Cayún, Juan Pablo; Krall Opazo, Paola Margarita; Quiñones Sepúlveda, Luis Abel (Frontiers Media, 2021)
      Cyclosporine (CsA) and tacrolimus (TAC) are immunosuppressant drugs characterized by a narrow therapeutic range and high pharmacokinetic variability. The effect of polymorphisms in genes related to the metabolism and ...
    • Graft versus host disease with oral involvement. Report of one case Enfermedad injerto contra huésped (EICH). ... 
      Rojas Alcayaga, Gonzalo; González, Néstor G.; Venables, Cristián G.; Araos, Daniel H. (2008)
      Graft versus Host Disease (GVHD) is a common complication in allogenic bone marrow transplants and in some cases, it involves the oral mucosa. Therefore, the appropriate diagnosis and timely treatment is essential to prevent ...
    • The advantages of polymeric hydrogels in calcineurin inhibitor delivery 
      Sandoval Yánez, Claudia; Escobar, Leslie; Amador, Cristian A. (MDPI, 2020)
      In recent years, polymeric hydrogels (PolyHy) have been extensively explored for their applications in biomedicine as biosensors, in tissue engineering, diagnostic processes, and drug release. The physical and chemical ...