Browsing by Subject "polymorphisms"

Now showing items 1-3 of 3

    • Correlates of efavirenz exposure in chilean patients affected with human immunodeficiency virus reveals a ... 
      Cortés Moncada, Claudia; Siccardi, Marco; Chaikan, Ammara; Owen, Andrew; Zhang, Guijun; Porte, Charles J L La (2013)
      OBJECTIVE: To explore the effect of demographics and single-nucleotide polymorphisms in cytochrome P450 (CYP) 2B6, 2A6, UDP-glucuronosyltransferase (UGT) 2B7, and the constitutive androstane receptor (CAR) genes on efavirenz ...
    • Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs ... 
      Roco Arriagada, Angela Margarita; Quiñones Sepúlveda, Luis; Agúndez, José A. G.; García Martin, Elena; Squicciarini Rueda, Valentina; Miranda Melo, Carla Estefanía; Garay, Joselyn; Farfán, Nancy; Saavedra Saavedra, Iván; Cáceres Lillo, Dante; Ibarra, Carol; Varela Figueroa, Nelson (2012)
      Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases. Most of the antineoplastic drugs are ...
    • Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, ... 
      Espinosa-Parrilla, Yolanda; Muñoz, Xavier; Bonet, Catalina; Garcia, Nadia; Venceslá, Adoraciõn; Yiannakouris, Nikos; Naccarati, Alessio; Sieri, Sabina; Panico, Salvatore; Huerta, José M.; Barricarte, Aurelio; Menéndez, Virginia; Sánchez-Cantalejo, Emilio; Dorronsoro, (Wiley-Liss Inc., 2014)
      MicroRNAs (miRNAs) are post-transcriptional gene regulators involved in a wide range of biological processes including tumorigenesis. Deregulation of miRNA pathways has been associated with cancer but the contribution of ...