Browsing by Author "XX600826"

Now showing items 1-20 of 55

    • Activation of RANKL-induced osteoclasts and memory T lymphocytes by Porphyromonas gingivalis is serotype dependant 
      Vernal Astudillo, Rolando; Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Pujol, Myriam; Díaz Guerra, Eva; Silva, Augusto; Sanz, Mariano; García Sanz, José (Blackwell Munksgaard, 2014)
      Aim: Destructive periodontitis is associated with a Th1–Th17 immune response and activation of RANKL-induced osteoclasts. In addition, Porphyromonas gingivalis K1 and K2 serotypes induce a strong Th1–Th17 response. This ...
    • Aggregatibacter actinomycetemcomitans Induces Autophagy in Human Junctional Epithelium Keratinocytes 
      Vicencio, Emiliano; Cordero, Esteban M.; Cortés, Bastián I.; Palominos, Sebastián; Parra, Pedro; Mella, Tania; Henrríquez, Constanza; Salazar, Nelda; Monasterio Ocares, Gustavo; Cafferata, Emilio A.; Murgas, Paola; Vernal Astudillo, Rolando; Cortez, Cristian (MDPI, 2020)
      The adverse environmental conditions found in the periodontium during periodontitis pathogenesis stimulate local autophagy responses, mainly due to a continuous inflammatory response against the dysbiotic subgingival ...
    • Alveolar bone resorption and TH1/TH17-associated immune response triggered during Aggregatibacter ... 
      Monasterio, Gustavo; Castillo, Francisca; Ibarra, Juan; Guevara, José; Rojas, Leticia; Alvarez, Carla; Fernández, Baltasar; Agüero, Amaru; Betancur, Daniel; Vernal Astudillo, Rolando (Wiley-Blackwell, 2018)
      BACKGROUND: Aggregatibacter actinomycetemcomitans expresses several virulence factors that may contribute to the pathogenesis of periodontitis. Based on the antigenicity of the O-polysaccharide component of the ...
    • Asociación de mayores niveles de RANKL y linfocitos T CD4+ en periodontitis 
      Vernal Astudillo, Rolando; Chaparro, Alejandra; Dutzan Muñoz, Nicolás; Chandía Espinosa, Sabrita; Puente Piccardo, Javier; Silva, Augusto; Gamonal Aravena, Jorge Antonio (Escuela de Odontología. Facultad de Salud. Universidad del Valle, 2004)
      Propósito: La periodontitis es una enfermedad infecciosa que involucra una sobre-respuesta inmune del hospedero y se caracteriza por la destrucción de los tejidos de soporte del diente.Durante su desarrollo se establece ...
    • ATP Induces IL-1 β Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related ... 
      Garciá, Killen; Escobar, Gisselle; Mendoza, Pablo; Beltran, Caroll; Pérez, Claudio; Arancibia, Sergio; Vernal Astudillo, Rolando; Rodas, Paula; Acunã-Castillo, Claudio; Escobar, Alejandro (Hindawi Limited, 2016)
      Neisseria gonorrhoeae (Ngo) has developed multiple immune evasion mechanisms involving the innate and adaptive immune responses. Recent findings have reported that Ngo reduces the IL-1𝛽 secretion of infected human ...
    • Biochemical markers of bone metabolism in gingival crevicular fluid during early orthodontic tooth movement 
      Barbieri, German; Solano, Patricia; Alarcón, José Antonio; Vernal Astudillo, Rolando; Rios Lugo, Judith; Sanz, Mariano; Martín, Conchita (The EH Angle Education and Research Foundation, 2013)
      Objective: To evaluate the expression of an activator of nuclear factor-kappa (RANK), osteoprotegerin (OPG), osteopontin (OPN), and transforming growth factor ß1 (TGF-ß1) in gingival crevicular fluid (GCF) of teeth ...
    • Boldine inhibits the alveolar bone resorption during ligature-induced periodontitis by modulating the ... 
      Cafferatta Chea, Emilio; Castro Saavedra, Sebastián; Fuentes Barros, Gonzalo; Melgar Rodríguez, Samanta; Rivera Rodríguez, Felipe; Carvajal Pavez, Paola; Hernández Ríos, Emma; Cortés, Bastián; Cortez, Cristian; Cassels Niven, Bruce; Vernal Astudillo, Rolando (Wiley, 2020)
      Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ...
    • Bone resorptive activity in symptomatic and asymptomatic apical lesions of endodontic origin 
      Salinas Muñoz, M.; Garrido Flores, Carlos; Baeza Paredes, Mauricio; Huaman Chipana, P.; García Sesnich, Jocelyn; Bologna, R.; Vernal Astudillo, Rolando; Hernández, M. (Springer, 2017)
      The aim of this study is to assess the levels and diagnostic accuracy of a set of bone resorption biomarkers, including TRAP-5, RANKL, and OPG in symptomatic and asymptomatic apical lesions and controls. Apical tissues ...
    • Brucella canis induces canine CD4 + T cells multi-cytokine Th1/Th17 production via dendritic cell activation 
      Pujol, Myriam; Borie Polanco, Consuelo; Montoya, María; Ferreira, Arturo; Vernal Astudillo, Rolando (Elsevier, 2019)
      Brucella canis is a small intracellular Gram-negative bacterium that frequently leads to chronic infections highly resistant to antibiotic therapy in dogs. Also, it causes mild human brucellosis compared to other zoonotic ...
    • CCL2 Inhibits the Apoptosis Program Induced by Growth Factor Deprivation, Rescuing Functional T Cells 
      Díaz Guerra, Eva; Vernal Astudillo, Rolando; Prete, M. Julieta del; Silva, Augusto; García Sanz, José A. (American Association of Immunologists, 2007)
      The precise mechanisms involved in the switch between the clonal expansion and contraction phases of a CD8 T cell response remain to be fully elucidated. One of the mechanisms implicated in the contraction phase is ...
    • CCR7 in periodontal lymphoid-like structures formation 
      Álvarez Rivas, C.; Rojas, L.; Monasterio, G.; García, K.; Pujol, M.; Carvajal, P.; Vernal Astudillo, Rolando (2016)
    • Development of a self report questionnaire designed for population based surveillance of gingivitis in ... 
      Quiróz, Viviana; Reinero Núñez, Daniela; Hernández Ríos, Patricia; Contreras Balbontín, Johanna; Vernal Astudillo, Rolando; Carvajal, Paola (Universidade de São Paulo, 2017)
      The major infectious diseases in Chile encompass the periodontal diseases, with a combined prevalence that rises up to 90% of the population. Thus, the population-based surveillance of periodontal diseases plays a central ...
    • Differential cytokine expression by human dendritic cells in response to different Porphyromonas gingivalis ... 
      Vernal Astudillo, Rolando; León, Rubén; Silva, Augusto; Van Winkelhoff, Arie; García Sanz, José; Sanz, Mariano (2009)
      Aim: Capsular polysaccharides play an important role in the virulence of Grampositive and Gram-negative bacteria. In Porphyromonas gingivalis, six serotypes have been described based on capsular antigenicity and its ...
    • Differential human Th22-lymphocyte response triggered by Aggregatibacter actinomycetemcomitans serotypes 
      Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Monasterio, Gustavo; Pujol, Myriam; Rojas, Leticia; Alvarez, Carla; Carvajal, Paola; Vernal Astudillo, Rolando (Elsevier Ltd, 2017)
      Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on lipopolysaccharide (LPS) antigenicity. When T lymphocytes were stimulated with these serotypes, different patterns of ...
    • Differential response of dendritic cells upon co-infection with different Aggregatibacter actinomycetemcomitans ... 
      Rojas, L.; Álvarez, C.; Melgar Rodríguez, Samanta Azucena; Pujol, M.; Monasterio, G.; García, K.; Díaz Zúñiga, J.; Fariña, V.; Hernández, M.; Vernal Astudillo, Rolando (2016)
    • Distinct human T-lymphocyte responses triggered by Porphyromonas gingivalis capsular serotypes 
      Vernal Astudillo, Rolando; Diaz Guerra, Eva; Silva, Augusto; Sanz, Mariano; García Sanz, José A. (John Wiley & Sons, 2014)
      Aim: Porphyromonas gingivalis can synthesize an extracellular capsule and different serotypes have been described based on capsular antigenicity. On dendritic cells (DCs), the type of capsule present plays a role on the ...
    • Does the Use of a ''walking bleaching'' technique increase bone resorption markers? 
      Bersezio Miranda, Cristian; Vildósola Grez, Patricio; Sáez, M.; Sánchez, F.; Vernal Astudillo, Rolando; Oliveira, Osmir; Jorquera, G.; Basualdo, J.; Loguercio, A.; Fernández Godoy, Eduardo (Indiana University School of Dentistry, 2018)
      Objective: This randomized clinical trial evaluated the effect of 35% hydrogen peroxide in comparison with 37% carbamide peroxide in a nonvital bleaching technique of ‘‘walking bleaching’’ (four sessions of treatment) ...
    • Effectiveness and impact of the walking bleach technique on esthetic self-perception and psychosocial ... 
      Bersezio Miranda, Cristian; Martin, J.; Peña, F.; Rubio, M.; Estay, J.; Vernal Astudillo, Rolando; Oliveira Junior, Osmir; Fernández Godoy, Eduardo (Indiana University School of Dentistry, 2017)
      Objective: This trial evaluates the impact of psychosocial and esthetic self-perceptions of patients undergoing nonvital tooth bleaching using the walking bleach technique. We also assessed the clinical effectiveness ...
    • Expression of proinflammatory cytokines in osteoarthritis of the temporomandibular joint 
      Vernal Astudillo, Rolando; Velásquez, Edgar; Gamonal Aravena, Jorge Antonio; García Sanz, José A.; Silva, Augusto; Sanz, Mariano (PERGAMON-ELSEVIER SCIENCE LTD, 2008-10)
      Objective: This study reports the expression of proinflammatory cytokines in temporomandibular joint (TMJ) of patients affected with temporomandibular osteoarthritis (OA). Design: In twelve OA of the TMJ (OA–TMJ) affected ...
    • H2O2 activates matrix metalloproteinases through the nuclear factor kappa B pathway and Ca2+ signals in ... 
      Osorio, C.; Cavalla, F.; Paula Lima, Andrea; Díaz Araya, Guillermo; Vernal Astudillo, Rolando; Ahumada, P.; Gamonal Aravena, Jorge Antonio; Hernández, M. (Wiley & Sons, 2015)
      BackgroundThe mechanisms involved in reactive oxygen species and matrix metalloproteinase (MMP)-mediated periodontal tissue breakdown are unknown. ObjectiveTo determine the effect of H2O2 in MMP-2 and MMP-9 activity, ...