Browsing by Subject "Periodontitis"

Now showing items 1-20 of 37

    • Activation of RANKL-induced osteoclasts and memory T lymphocytes by Porphyromonas gingivalis is serotype dependant 
      Vernal Astudillo, Rolando; Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Pujol, Myriam; Díaz Guerra, Eva; Silva, Augusto; Sanz, Mariano; García Sanz, José (Blackwell Munksgaard, 2014)
      Aim: Destructive periodontitis is associated with a Th1–Th17 immune response and activation of RANKL-induced osteoclasts. In addition, Porphyromonas gingivalis K1 and K2 serotypes induce a strong Th1–Th17 response. This ...
    • Active MMP-8 quantitative test as an adjunctive tool for early diagnosis of periodontitis 
      Hernández Ríos, Marcela; Baeza Paredes, Mauricio Enrique; Raisanen, Ismo; Contreras Balbontín, Johanna; Tervahartiala, Taina; Chaparro, Alejandra; Sorsa, Timo; Hernández Ríos, Patricia (MDPI, 2021)
      Periodontitis is a host-mediated bacterial disease that affects the tooth attachment apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical diagnosis. This study aimed to evaluate the diagnostic ...
    • Alzheimer's Disease-Like Pathology Triggered by Porphyromonas gingivalis in Wild Type Rats Is Serotype Dependent 
      Díaz Zúñiga, Jaime; More, Jamileth Y.; Melgar Rodríguez, Samanta; Jiménez Unión, Matías; Villalobos Orchard, Francisca; Muñoz Manríquez, Constanza; Monasterio, Gustavo; Valdés Guerrero, José; Vernal, Rolando; Paula-Lima, Andrea (Frontiers Media, 2020)
      Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota that colonizes the gingivodental sulcus. ...
    • Asociación de mayores niveles de RANKL y linfocitos T CD4+ en periodontitis 
      Vernal Astudillo, Rolando; Chaparro, Alejandra; Dutzan Muñoz, Nicolás; Chandía Espinosa, Sabrita; Puente Piccardo, Javier; Silva, Augusto; Gamonal Aravena, Jorge Antonio (Escuela de Odontología. Facultad de Salud. Universidad del Valle, 2004)
      Propósito: La periodontitis es una enfermedad infecciosa que involucra una sobre-respuesta inmune del hospedero y se caracteriza por la destrucción de los tejidos de soporte del diente.Durante su desarrollo se establece ...
    • Assessment of cardiovascular risk in women with periodontal diseases according to c-reactive protein levels 
      Da Venezia, Claudia; Hussein Rojas, Nayib Ignacio; Hernández Ríos, Marcela; Contreras Balbontín, Johanna; Morales Chvets, Alicia Alvarovna; Valdés, Macarena; Rojas, Francisca; Matamala López, Loreto; Hernández Ríos, Patricia (MDPI, 2021)
      Cardiovascular diseases (CVD) are highly prevalent non-communicable diseases worldwide. Periodontitis may act as a non-traditional cardiovascular risk (CVR) factor, linked by a low-grade systemic inflammation mediated by ...
    • Association of interleukin-1 gene variations with moderate to severe chronic periodontitis in multiple ethnicities 
      Wu, X.; Offenbacher, S.; López Villarroel, Néstor; Chen, D.; Wang, H.-Y.; Rogus, J.; Zhou, J.; Beck, J.; Jiang, S.; Bao, X.; Wilkins, L.; Doucette Stamm, L.; Kornman, K. (John Wiley, 2015)
      Background and Objective: Genetic markers associated with disease are often non-functional and generally tag one or more functional "causative" variants in linkage disequilibrium. Markers may not show tight linkage to the ...
    • Autophagy in aging-related oral diseases 
      Peña Oyarzún, Daniel; San Martin, Carla; Hernández Cáceres, María Paz; Lavandero González, Sergio Alejandro; Morselli, Eugenia; Budini Budini, Mauricio Fernando; Burgos, Patricia V.; Criollo Céspedes, Alfredo Guillermo (Frontiers Media, 2022)
      Autophagy is an intracellular degradation mechanism that allows recycling of organelles and macromolecules. Autophagic function increases metabolite availability modulating metabolic pathways, differentiation and cell ...
    • Biomarkers in gingival crevicular fluid: Review of literature 
      Quesada, Jorge; Rivera Alvarez, Sonia (Universidad Costa Rica, Facultad odontología, 2017)
      Biomarkers are molecules that can be objectively measured and evaluated as indicators of normal biological processes, pathological processes or pharmacological responses to therapeutic intervention. In the crevicular ...
    • Boldine inhibits the alveolar bone resorption during ligature-induced periodontitis by modulating the ... 
      Cafferatta Chea, Emilio; Castro Saavedra, Sebastián; Fuentes Barros, Gonzalo; Melgar Rodríguez, Samanta; Rivera Rodríguez, Felipe; Carvajal Pavez, Paola; Hernández Ríos, Emma; Cortés, Bastián; Cortez, Cristian; Cassels Niven, Bruce; Vernal Astudillo, Rolando (Wiley, 2020)
      Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ...
    • CCR5 Delta 32 (rs333) polymorphism is associated with decreased risk of chronic and aggressive periodontitis: ... 
      Cavalla Ruiz, Ian Franco; Biguetti, Claudia C.; Dionisio, Thiago J.; Azevedo, Michelle C. S.; Martins, Walter, Jr.; Santos, Carlos F.; Trombone, Ana Paula F.; Silva, Renato M.; Letra, Ariadne; Garlet, Gustavo P. (Elsevier, 2018)
      Chronic and aggressive periodontitis are infectious diseases characterized by the irreversible destruction of periodontal tissues, which is mediated by the host inflammatory immune response triggered by periodontal infection. ...
    • Clinical effects of probiotic or azithromycin as an adjunct to scaling and root planning in the treatment ... 
      Morales Chvets, Alicia Alvarovna; Contador Cotroneo, Rafael Ignacio; Bravo, Joel; Carvajal Pavez, Paola Lorena; Silva, Nora; Strauss Avendaño, Franz Josef; Gamonal Aravena, Jorge Antonio (BMC, 2021)
      Background: The aim of this triple-blind placebo-controlled parallel-arm randomized clinical trial was to evaluate the clinical effects of Lactobacillus rhamnosus SP1 or azithromycin as an adjunct to scaling and root ...
    • Cuantificación de la quimiocina CCL5 en pacientes con diabetes mellitus tipo 2 y/o periodontitis cronica: ... 
      Sansores España, Luis; Carrillo Avila, Arelly; Sauri Esquivel, Eduard; Guzmán Marín, Eugenia; Hernández Ríos, Emma; Pozos Guillén, Amaury; Martínez Aguilar, Víctor (Universidad Costa Rica, Facultad odontología, 2017)
      El propósito del presente estudio fue cuantificar la presencia de la quimiocina CCL5 (RANTES) en Líquido Crevicular Gingival (LCG) de pacientes con Periodontitis Crónica (PC) y/o Diabetes Mellitus tipo 2 (DM2). Se realizó ...
    • Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and −9 are associated with ... 
      Chaparro, Alejandra; Realini, Ornella; Hernández Ríos, Marcela; Albers, Daniela; Weber, Laura; Ramírez, Valeria; Param, Fernanda; Kusanovic, Juan Pedro; Sorsa, Timo; Rice, Gregory Edward; Illanes, Sebastián E. (Wiley, 2020)
      Background Gestational diabetes mellitus (GDM) is increasing worldwide and women with a history of GDM are at risk of developing type 2 diabetes which is a risk factor for periodontitis. Aim To explore the association ...
    • Editorial: The human microbiota in periodontitis 
      Hernández Ríos, Emma Marcela; Alves Mayer, Marcia Pinto; Santi Rocca, Julien (Frontiers Media, 2022)
    • Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis 
      Baeza Paredes, Mauricio; Morales Chvets, Alicia; Cisterna Vergara, Patricio; Cavalla Ruiz, Ian Franco; Jara Bahamondes, Gisela; Isamitt Parra, Yuri; Pino Zúñiga, Hilda; Gamonal Aravena, Jorge (Univ Sao Paulo Fac Odontologia Bauru, 2020)
      The evidence is inconclusive regarding the effect of periodontal treatment on glycemic control and systemic inflammation in patients with type 2 diabetes (T2D) and periodontitis Objective: To evaluate the effect of scaling ...
    • Effects of short-chain fatty acids on human oral epithelial cells and the potential impact on periodontal ... 
      Magrin, Gabriel Leonardo; Strauss Avendaño, Franz; Magalhães Benfatti, César Augusto; Cople Maia, Lucianne; Gruber, Reinhard (MDPI, 2020)
      Short-chain fatty acids (SCFA), bacterial metabolites released from dental biofilm, are supposed to target the oral epithelium. There is, however, no consensus on how SCFA affect the oral epithelial cells. The objective ...
    • Efficacy of laser monotherapy or non-surgical mechanical instrumentation in the management of untreated ... 
      Lin, Zhikai; Strauss Avendaño, Franz; Lang, Niklaus P; Sculean, Anton; Salvi, Giovanni E.; Stahli, Alexandra (Springer, 2020)
      Objective To evaluate and compare the effects of laser monotherapy with non-surgical mechanical instrumentation alone in untreated periodontitis patients. Materials and methods A focused question was formulated based on ...
    • Exploring the expression of pro-inflammatory and hypoxia-related microRNA-20a, MicroRNA-30e, and microRNA-93 ... 
      Chaparro, Alejandra; Lozano, Mauricio; Gaedechens, Dominique; López, Carolina; Albers, Daniela; Hernández Ríos, Emma Marcela; Pascual, Andrés; Nart, José; Irarrazabal, Carlos E. (MDPI, 2022)
      Hypoxia associated with inflammation are common hallmarks observed in several diseases, and it plays a major role in the expression of non-coding RNAs, including microRNAs (miRNAs). In addition, the miRNA target genes for ...
    • Gingival crevicular fluid as biomarker’s source for Alzheimer’s disease 
      Sansores España, Luis; Morales Lara, Francisca; Arriola Pacheco, Fabio; Astorga, Jessica; Paula Lima, Andrea; Carrillo Ávila, Arelly; Melgar Rodríguez, Samanta; Martínez Aguilar, Víctor; Díaz Zúñiga, Jaime (Universidad Costa Rica, Facultad Odontología, 2022)
      Periodontitis is a low-grade inflammatory disease caused by a subgingival dysbiotic microbiota. Multiple studies have determined the higher prevalence of tooth loss and poor oral hygiene in patients with Alzheimer's disease ...
    • Host response mechanisms in periodontal diseases 
      Silva, Nora; Abusleme Ramos, Loreto Andrea; Bravo, Denisse; Dutzan Muñoz, Nicolás; García Sesnich, Jocelyn; Vernal Astudillo, Rolando; Hernández, Marcela; Gamonal Aravena, Jorge Antonio (Univ Sao Paulo Fac Odontologia Bauru, 2015)
      Periodontal diseases usually refer to common inflammatory disorders known as gingivitis and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm, including Porphyromonas gingivalis, ...