Prediction of protein retention in hydrophobic interaction chromatography

Author	dc.contributor.author	Mahn Osses, Andrea
Author	dc.contributor.author	Asenjo de Leuze, Juan	es_CL
Admission date	dc.date.accessioned	2007-05-18T19:27:43Z
Available date	dc.date.available	2007-05-18T19:27:43Z
Publication date	dc.date.issued	2005-07
Cita de ítem	dc.identifier.citation	BIOTECHNOLOGY ADVANCES 23 (5): 359-368 JUL 2005	en
Identifier	dc.identifier.issn	0734-9750
Identifier	dc.identifier.uri	https://repositorio.uchile.cl/handle/2250/127197
Abstract	dc.description.abstract	Hydrophobic interaction chromatography (HIC) is a powerful technique for protein separation. This review examines methodologies for predicting protein retention time in HIC involving elution with salt gradients. The methodologies discussed consider three-dimensional structure data of the protein and its surface hydrophobicity. Despite their limitations, the methods discussed are useful in designing purification processes for proteins and easing the tedious experimental work that is currently required for developing purification protocols.	en
Lenguage	dc.language.iso	en	en
Publisher	dc.publisher	PERGAMON-ELSEVIER SCIENCE	en
Keywords	dc.subject	DOCKING	en
Título	dc.title	Prediction of protein retention in hydrophobic interaction chromatography	en
Document type	dc.type	Artículo de revista