| Author | dc.contributor.author | Campero Soffia, Mario | es_CL |
| Author | dc.contributor.author | Bostock, Hugh | |
| Admission date | dc.date.accessioned | 2010-06-16T13:57:20Z | |
| Available date | dc.date.available | 2010-06-16T13:57:20Z | |
| Publication date | dc.date.issued | 2010 | |
| Cita de ítem | dc.identifier.citation | Neuroscience Letters 470 (2010) 188–192 | en_US |
| Identifier | dc.identifier.other | doi:10.1016/j.neulet.2009.06.089 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/128560 | |
| Abstract | dc.description.abstract | In humans, there are different types of cutaneous cold-sensitive afferents responsible for cold sensation
and cold pain. Innocuous cold is primarily mediated by a population of slow A delta afferents, based
on psychophysical and neurophysiological studies. Noxious cold (usually below 15 ◦C) is mediated, at
least in part, by polymodal nociceptors. There is also a population of unmyelinated afferents responsive
to innocuous low temperature, some of which also respond to heat, whose sensory function has not
been completely defined. A paradoxical hot/burning evoked by cooling is unmasked by A-fibre block,
and similar sensations are evoked by applying simultaneous cool and warm stimuli to adjacent skin
areas. These unmyelinated fibres activated by innocuous cooling (and heating) may contribute to this
hot/burning sensation, along with other thermoregulatory functions. | en_US |
| Patrocinador | dc.description.sponsorship | This work has been partially supported by NIH Grant
5R01NS048932-03. | en_US |
| Lenguage | dc.language.iso | en | en_US |
| Publisher | dc.publisher | ELSEVIER | en_US |
| Keywords | dc.subject | Cold fibres | en_US |
| Título | dc.title | Unmyelinated afferents in human skin and their responsiveness to low temperature | en_US |
| Document type | dc.type | Artículo de revista | |
