Prospective Evaluation of a Model of Prediction of Invasive Bacterial Infection Risk among Children with Cancer, Fever, and Neutropenia
Author | dc.contributor.author | Santolaya de Pablo, María Elena | |
Author | dc.contributor.author | Alvarez, Ana M. | es_CL |
Author | dc.contributor.author | Avilés, Carmen L. | es_CL |
Author | dc.contributor.author | Becker, Ana | es_CL |
Author | dc.contributor.author | Cofré, José | es_CL |
Author | dc.contributor.author | Enríquez, N. | es_CL |
Author | dc.contributor.author | O'Ryan Gallardo, Miguel | es_CL |
Author | dc.contributor.author | Payá, Ernesto | es_CL |
Author | dc.contributor.author | Salgado, Carmen | es_CL |
Author | dc.contributor.author | Silva, Pamela | es_CL |
Author | dc.contributor.author | Tordecilla, Juan | es_CL |
Author | dc.contributor.author | Varas P., Mónica | es_CL |
Author | dc.contributor.author | Villarroel, Milena | es_CL |
Author | dc.contributor.author | Viviani, Tamara | es_CL |
Author | dc.contributor.author | Zubieta, Marcela | es_CL |
Admission date | dc.date.accessioned | 2010-07-30T18:51:59Z | |
Available date | dc.date.available | 2010-07-30T18:51:59Z | |
Publication date | dc.date.issued | 2002 | |
Cita de ítem | dc.identifier.citation | Clinical Infectious Diseases 2002; 35:678–83 | en_US |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/128733 | |
Abstract | dc.description.abstract | A risk prediction model for invasive bacterial infection (IBI) was prospectively evaluated among children presenting with cancer, fever, and neutropenia. The model incorporated assessment of 5 previously identified risk factors: serum level of C-reactive protein (CRP) 90 mg/L, hypotension, identification of relapse of leukemia as the cancer type, platelet count of 50,000 platelets/mm3, and recent receipt of chemotherapy [16]. Children were uniformly evaluated at enrollment and were classified as having high or low risk for IBI according to a model that considers the number and type of variables present. Of the 263 febrile episodes evaluated during a 17-month period, 140 (53%) were in IBI-positive children. The sensitivity, specificity, and positive and negative predictive values of the model were 92%, 76%, 82%, and 90%, respectively. Identification of these 5 risk factors during the first 24 h of hospitalization was helpful in discriminating between children with a high or low risk for IBI. | en_US |
Patrocinador | dc.description.sponsorship | Financial support: Proyecto FONDECYT grant 1000680. | en_US |
Lenguage | dc.language.iso | en | en_US |
Título | dc.title | Prospective Evaluation of a Model of Prediction of Invasive Bacterial Infection Risk among Children with Cancer, Fever, and Neutropenia | en_US |
Document type | dc.type | Artículo de revista |
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