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Polycystic ovarian morphology in postmenarchal adolescents

Authordc.contributor.authorCodner Dujovne, Ethel 
Authordc.contributor.authorVillarroel, Claudio es_CL
Authordc.contributor.authorEyzaguirre, Francisca es_CL
Authordc.contributor.authorLópez, Patricia es_CL
Authordc.contributor.authorMerino, Paulina es_CL
Authordc.contributor.authorPérez Bravo, Francisco es_CL
Authordc.contributor.authorIñíguez Vila, Germán es_CL
Authordc.contributor.authorCassorla Goluboff, Fernando es_CL
Cita de ítemdc.identifier.citationFertility and Sterility, Vol. 95, No. 2, February 2011es_CL
General notedc.descriptionArtículo de publicación ISI.es_CL
Abstractdc.description.abstractObjective: To evaluate the association of polycystic ovary morphology (PCOM) with ovarian function in adolescents and to determine its time course during two years of follow-up. Design: Prospective study. Setting: Academic center. Patient(s): Twenty healthy adolescents were followed from 2–4 years after menarche. Intervention(s): We performed annual ultrasonographic and hormonal studies. Ovulation was assessed during 6 consecutive months by measuring salivary progesterone levels. Main Outcome Measure(s): Persistence of PCOM during the years following menarche; ovulation in girls with PCOM. Result(s): PCOM was observed in 40%, 35%, and 33.3% of the ultrasonographic studies performed at 2, 3, and 4 years after menarche, respectively. The concordance between ultrasonographic diagnosis at 2 and 4 years postmenarche (50%) was nonsignificant (kappa ¼ 0.08). PCOM was not associated with abnormalities in ovulatory rate, menstrual cycle duration, lipid levels, or homeostatic model assessment of insulin resistance. However, lower FSH (4.8 1.3 vs. 6.1 1.9 mUI/ml) were observed in girls with PCOM compared with those without PCOM. Similar T and stimulated 17-hydroxyprogesterone on the leuprolide test were observed in girls with and without PCOM. Conclusion(s): PCOM is an inconstant finding in healthy adolescents and does not appear to be associated with decreased ovulatory rate or metabolic abnormalities in healthy adolescents. This finding suggests that PCOM may correspond to a physiologic condition during early adolescence.es_CL
Patrocinadordc.description.sponsorshipSupported in part by the Fondo Nacional de Desarrollo Cient ıfico y Tecnol ogico Grant No. 1050452 and 1100123 (to E.C).es_CL
Keywordsdc.subjectPolycystic ovary morphologyes_CL
Títulodc.titlePolycystic ovarian morphology in postmenarchal adolescentses_CL
Document typedc.typeArtículo de revistaes_CL

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