Polimorfismos cercanos al gen IL28B y su relación con la infección con el virus hepatitis B

Author	dc.contributor.author	Venegas Santos, Mauricio
Author	dc.contributor.author	Torres B., Claudio	es_CL
Author	dc.contributor.author	Brahm Barril, Javier	es_CL
Admission date	dc.date.accessioned	2013-08-28T20:38:47Z
Available date	dc.date.available	2013-08-28T20:38:47Z
Publication date	dc.date.issued	2012
Cita de ítem	dc.identifier.citation	Rev Hosp Clín Univ Chile 2012; 23: 340 - 45	en_US
Identifier	dc.identifier.uri	https://repositorio.uchile.cl/handle/2250/129062
Abstract	dc.description.abstract	Three top single-nucleotide polymorphisms (rs12979860, rs12980275 and rs8099917) near to IL28B gene have been associated to spontaneous or relate to treatment-induced hepatitis C virus clearence. The role of this polymorphism is less known in hepatitis B virus (HBV) infection. Some studies have been focused to relate IL28B variants and clinical course of HBV infection, found discordant results. In relation to treatment for HBV, it has been shown an association between IL28B polymorphisms and response to therapy with Peginterferon.	en_US
Lenguage	dc.language.iso	es	en_US
Título	dc.title	Polimorfismos cercanos al gen IL28B y su relación con la infección con el virus hepatitis B	en_US
Document type	dc.type	Artículo de revista