Sonographic Measurement of the Quadriceps Muscle in Patients With Chronic Obstructive Pulmonary Disease
Author
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Cruz Montecinos, Carlos
Author
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Guajardo Rojas, Carlos
Author
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Montt, Eloísa
Author
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Contreras Briceño, Felipe
Author
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Torres Castro, Rodrigo
Author
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Díaz, Orlando
Author
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Cuesta Vargas, Antonio
Admission date
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2017-11-20T18:48:27Z
Available date
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2017-11-20T18:48:27Z
Publication date
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2016
Cita de ítem
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J Ultrasound Med 2016; 35:2405–2412 | 0278-4297
es_ES
Identifier
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10.7863/ultra.15.11032
Identifier
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https://repositorio.uchile.cl/handle/2250/145683
Abstract
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Objectives-The purpose of this study was to determine the association between functionality as assessed by the 6-minute walking test (6MWT), maximal voluntary contraction of the quadriceps (MVCQ), and quadriceps thickness and echo intensity as measured by sonography, in patients with chronic obstructive pulmonary disease (COPD).
Methods-Maximal voluntary contraction of the quadriceps and the thickness and echo intensity of the rectus femoris and vastus intermedius were evaluated in 20 patients with COPD. Functionality was assessed by the 6MWT. Differences between the evaluated muscles were determined by the Student t test. Pearson and Spearman rank correlation coefficients were used to analyze relationships between variables of interest, according to data characteristics. Finally, multivariate regression models were applied.
Results-There was a positive correlation between MVCQ and rectus femoris and vastus intermedius thickness (r=0.427; P=.030; r=0.469; P=.018, respectively) and a negative correlation between MVCQ and rectus femoris and vastus intermedius echo intensity (r=-0.500; P=.012; r=-0.482; P=.016). No correlation was found between MVCQ and the 6MWT (r=0.319; P=.085). Multivariate regression analysis showed that the rectus femoris echo intensity, vastus intermedius echo intensity, and vastus intermedius thickness explained 70% of the variance in the distance walked during the 6MWT.
Conclusions-These results indicate that, in patients with COPD, both quadriceps force and exercise capacity are associated with quantitative (thickness) and qualitative (echo intensity) characteristics of the quadriceps. Consequently, comprehensive assessments of peripheral muscles should simultaneously include both measurements.