Ontogenic development of intestinal disaccharidases in the precocial rodent Octodon degus (Octodontidae)
Author
dc.contributor.author
Sabat Kirkwood, Alejandro Pablo
Author
dc.contributor.author
Veloso Iriarte, Claudio
Admission date
dc.date.accessioned
2019-01-29T13:47:38Z
Available date
dc.date.available
2019-01-29T13:47:38Z
Publication date
dc.date.issued
2003
Cita de ítem
dc.identifier.citation
Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology, Volumen 134, Issue 2, 2003, Pages 393-397
Identifier
dc.identifier.issn
10956433
Identifier
dc.identifier.other
10.1016/S1095-6433(02)00296-9
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/159775
Abstract
dc.description.abstract
We studied the ontogeny of the intestinal brush border disaccharidases sucrase and lactase in the precocial rodent Octodon degus. Sucrase hydrolyze sugars from plants while lactase hydrolyzes sugars from milk. Enzyme expression varied inversely with dietary changes according to the developmental pattern. All new-born pups had high lactase and low sucrase activities. Also, a negative correlation between sucrase and lactase activity was found, supporting the economic design hypothesis for the intestinal tract. Profiles for development of sucrase expression exhibit some differences among precocial species, and in O. degus is correlated with the slower transition from milk to solid food consumption at weaning.