Growth hormone in infant malnutrition: The arginine test in marasmus and kwashiorkor
Author
dc.contributor.author
Beas,
Author
dc.contributor.author
Contreras Contreras, Marlene Daniella
Author
dc.contributor.author
Maccioni, Cristóbal
Author
dc.contributor.author
Arenas, Sara
Admission date
dc.date.accessioned
2019-01-29T15:43:48Z
Available date
dc.date.available
2019-01-29T15:43:48Z
Publication date
dc.date.issued
1971
Cita de ítem
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British Journal of Nutrition, Volumen 26, Issue 2, 2018, Pages 169-175
Identifier
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14752662
Identifier
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00071145
Identifier
dc.identifier.other
10.1079/BJN19710023
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/162202
Abstract
dc.description.abstract
1. Experiments in children and in animals seem to demonstrate that in marasmic malnutrition there is a reduction in the secretion of growth hormone. To study this problem the fasting, resting plasma concentrations of growth hormone were determined, before, and 45 and 60 min after, stimulation with an intravenous dose of arginine, in six infants with marasmus, in six infants with kwashiorkor and in five normal infants. 2. The values of plasma growth hormone (4·5 ± 0·97 ng/ml) in marasmic infants were significantly (P < 0·001) lower than those of the controls (7·8 ± 2·6 ng/ml), and responded little to stimulation with arginine (5·1 and 5·8 ng/ml at 45 and 60 min respectively), in contrast to those in the control group, which rose to 16·4 and 14·6 ng/ml. In children with kwashiorkor the values were very variable, but generally high, and showed little response (25·6 ± 13·3 before and 25·0 ± 17·6 and 14·2 ± 5·3 ng/ml at 45 and 60 min after stimulation respectively). 3. These results demonst