Volumetric self-sampling of cervicovaginal fluid to determine potential fertility: A multicentre pre-effectiveness study of the Rovumeter®
Author
dc.contributor.author
Flynn, A. M.
Author
dc.contributor.author
Collins, W. P.
Author
dc.contributor.author
Royston, P.
Author
dc.contributor.author
Barbato, M.
Author
dc.contributor.author
Mena-Gonzalez, P.
Author
dc.contributor.author
Alliende, M. E.
Admission date
dc.date.accessioned
2019-01-29T15:55:02Z
Available date
dc.date.available
2019-01-29T15:55:02Z
Publication date
dc.date.issued
1997
Cita de ítem
dc.identifier.citation
Human Reproduction, Volumen 12, Issue 8, 2018, Pages 1826-1831
Identifier
dc.identifier.issn
02681161
Identifier
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10.1093/humrep/12.8.1826
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/162765
Abstract
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The aim of this study was to assess how effectively the Rovumeter®, designed for the volumetric self-sampling of cervicovaginal fluid (CVF), can be used to locate the minimum period of potential fertility (PPF) during ovulatory cycles. A multicentre, prospective study was undertaken of volunteers (attending natural family planning clinics) over three consecutive, apparently normal, menstrual cycles. All women collected daily samples of early morning urine and CVF and recorded the volumes (to the nearest 1.0 and 0.1 ml respectively). The concentrations of oestrone glucuronide (EG), luteinizing hormone (LH) and pregnanediol glucuronide (PG) were measured in all samples of early morning urine by immunoassay. A preliminary data set was used to optimize an algorithm to detect the start and end of potential fertility from the volumes of CVF. The end-points used were the normality of each menstrual cycle from its length, the length of luteal phase, and concentrations of EG, LH and PG, the sta